O95239: Chromosome-associated kinesin KIF4A

General Information

Protein names	- Chromosome-associated kinesin KIF4A - Chromokinesin-A
Gene names	KIF4A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95239

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MKEEVKGIPV RVALRCRPLV PKEISEGCQM CLSFVPGEPQ VVVGTDKSFT YDFVFDPSTE
        70         80         90        100        110        120
QEEVFNTAVA PLIKGVFKGY NATVLAYGQT GSGKTYSMGG AYTAEQENEP TVGVIPRVIQ
       130        140        150        160        170        180
LLFKEIDKKS DFEFTLKVSY LEIYNEEILD LLCPSREKAQ INIREDPKEG IKIVGLTEKT
       190        200        210        220        230        240
VLVALDTVSC LEQGNNSRTV ASTAMNSQSS RSHAIFTISL EQRKKSDKNS SFRSKLHLVD
       250        260        270        280        290        300
LAGSERQKKT KAEGDRLKEG ININRGLLCL GNVISALGDD KKGGFVPYRD SKLTRLLQDS
       310        320        330        340        350        360
LGGNSHTLMI ACVSPADSNL EETLNTLRYA DRARKIKNKP IVNIDPQTAE LNHLKQQVQQ
       370        380        390        400        410        420
LQVLLLQAHG GTLPGSITVE PSENLQSLME KNQSLVEENE KLSRGLSEAA GQTAQMLERI
       430        440        450        460        470        480
ILTEQANEKM NAKLEELRQH AACKLDLQKL VETLEDQELK ENVEIICNLQ QLITQLSDET
       490        500        510        520        530        540
VACMAAAIDT AVEQEAQVET SPETSRSSDA FTTQHALRQA QMSKELVELN KALALKEALA
       550        560        570        580        590        600
RKMTQNDSQL QPIQYQYQDN IKELELEVIN LQKEKEELVL ELQTAKKDAN QAKLSERRRK
       610        620        630        640        650        660
RLQELEGQIA DLKKKLNEQS KLLKLKESTE RTVSKLNQEI RMMKNQRVQL MRQMKEDAEK
       670        680        690        700        710        720
FRQWKQKKDK EVIQLKERDR KRQYELLKLE RNFQKQSNVL RRKTEEAAAA NKRLKDALQK
       730        740        750        760        770        780
QREVADKRKE TQSRGMEGTA ARVKNWLGNE IEVMVSTEEA KRHLNDLLED RKILAQDVAQ
       790        800        810        820        830        840
LKEKKESGEN PPPKLRRRTF SLTEVRGQVS ESEDSITKQI ESLETEMEFR SAQIADLQQK
       850        860        870        880        890        900
LLDAESEDRP KQRWENIATI LEAKCALKYL IGELVSSKIQ VSKLESSLKQ SKTSCADMQK
       910        920        930        940        950        960
MLFEERNHFA EIETELQAEL VRMEQQHQEK VLYLLSQLQQ SQMAEKQLEE SVSEKEQQLL
       970        980        990       1000       1010       1020
STLKCQDEEL EKMREVCEQN QQLLRENEII KQKLTLLQVA SRQKHLPKDT LLSPDSSFEY
      1030       1040       1050       1060       1070       1080
VPPKPKPSRV KEKFLEQSMD IEDLKYCSEH SVNEHEDGDG DDDEGDDEEW KPTKLVKVSR
      1090       1100       1110       1120       1130       1140
KNIQGCSCKG WCGNKQCGCR KQKSDCGVDC CCDPTKCRNR QQGKDSLGTV ERTQDSEGSF
      1150       1160       1170       1180       1190       1200
KLEDPTEVTP GLSFFNPVCA TPNSKILKEM CDVEQVLSKK TPPAPSPFDL PELKHVATEY
      1210       1220       1230
QENKAPGKKK KRALASNTSF FSGCSPIEEE AH

Isoforms

- Isoform 2 of Chromosome-associated kinesin KIF4A

Sequence View

        10         20         30         40         50         60
MKEEVKGIPV RVALRCRPLV PKEISEGCQM CLSFVPGEPQ VVVGTDKSFT YDFVFDPSTE
        70         80         90        100        110        120
QEEVFNTAVA PLIKGVFKGY NATVLAYGQT GSGKTYSMGG AYTAEQENEP TVGVIPRVIQ
       130        140        150        160        170        180
LLFKEIDKKS DFEFTLKVSY LEIYNEEILD LLCPSREKAQ INIREDPKEG IKIVGLTEKT
       190        200        210        220        230        240
VLVALDTVSC LEQGNNSRTV ASTAMNSQSS RSHAIFTISL EQRKKSDKNS SFRSKLHLVD
       250        260        270        280        290        300
LAGSERQKKT KAEGDRLKEG ININRGLLCL GNVISALGDD KKGGFVPYRD SKLTRLLQDS
       310        320        330        340        350        360
LGGNSHTLMI ACVSPADSNL EETLNTLRYA DRARKIKNKP IVNIDPQTAE LNHLKQQVQQ
       370        380        390        400        410        420
LQVLLLQAHG GTLPGSITVE PSENLQSLME KNQSLVEENE KLSRGLSEAA GQTAQMLERI
       430        440        450        460        470        480
ILTEQANEKM NAKLEELRQH AACKLDLQKL VETLEDQELK ENVEIICNLQ QLITQLSDET
       490        500        510        520        530        540
VACMAAAIDT AVEQEAQVET SPETSRSSDA FTTQHALRQA QMSKELVELN KALALKEALA
       550        560        570        580        590        600
RKMTQNDSQL QPIQYQYQDN IKELELEVIN LQKEKEELVL ELQTAKKDAN QAKLSERRRK
       610        620        630        640        650        660
RLQELEGQIA DLKKKLNEQS KLLKLKESTE RTVSKLNQEI RMMKNQRVQL MRQMKEDAEK
       670        680        690        700        710        720
FRQWKQKKDK EVIQLKERDR KRQYELLKLE RNFQKQSNVL RRKTEEAAAA NKRLKDALQK
       730        740        750        760        770        780
QREVADKRKE TQSRGMEGTA ARVKNWLGNE IEVMVSTEEA KRHLNDLLED RKILAQDVAQ
       790        800        810        820        830        840
LKEKKESGEN PPPKLRRRTF SLTEVRGQVS ESEDSITKQI ESLETEMEFR SAQIADLQQK
       850        860        870        880        890        900
LLDAESEDRP KQRWENIATI LEAKCALKYL IGELVSSKIQ VSKLESSLKQ SKTSCADMQK
       910        920        930        940        950        960
MLFEERNHFA EIETELQAEL VRMEQQHQEK VLYLLSQLQQ SQMAEKQLEE SVSEKEQQLL
       970        980        990       1000       1010       1020
STLKCQDEEL EKMREVCEQN QQLLRENEII KQKLTLLQVA SRQKHLPKDT LLSPDSSFEY
      1030       1040       1050       1060       1070       1080
VPPKPKPSRV KEKFLEQSMD IEDLKYCSEH SVNEHEDGDG DDDEGDDEEW KPTKLVKVSR
      1090       1100       1110       1120       1130       1140
KNIQGCSCKG WCGNKQCGCR KQKSDCGVDC CCDPTKCRNR QQGKDSLGTV ERTQDSEGSF
      1150       1160       1170       1180       1190       1200
KLEDPTEVTP GLSFFNPVCA TPNSKILKEM CDVEQVLSKK TPPAPSPFDL PELKHVATEY
      1210       1220       1230
QENKAPGKKK KRALASNTSF FSGCSPIEEE AH

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O95239-1-unknown	MKEEVK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95239-1-unknown	MKEEVK...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78988
O95239-1-unknown	MKEEVK...	1		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O95239-1-	MKEEVK...	1		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O95239-1-	MKEEVK...	1		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O95239-183-unknown	VALDTV...	183	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13874
O95239-183-unknown	VALDTV...	183	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145993

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EKTVLV	182	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13874
...EKTVLV	182	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129292
...EEEAH	1232	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

O95239: Chromosome-associated kinesin KIF4A

General Information

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates