P52756: RNA-binding protein 5

General Information

Protein names	- RNA-binding protein 5 - Protein G15 - Putative tumor suppressor LUCA15 - RNA-binding motif protein 5 - Renal carcinoma antigen NY-REN-9
Gene names	RBM5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P52756

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of RNA-binding protein 5 - Isoform 3 of RNA-binding protein 5 - Isoform 4 of RNA-binding protein 5 - Isoform 5 of RNA-binding protein 5

Sequence View

        10         20         30         40         50         60
MGSDKRVSRT ERSGRYGSII DRDDRDERES RSRRRDSDYK RSSDDRRGDR YDDYRDYDSP
        70         80         90        100        110        120
ERERERRNSD RSEDGYHSDG DYGEHDYRHD ISDERESKTI MLRGLPITIT ESDIREMMES
       130        140        150        160        170        180
FEGPQPADVR LMKRKTGVSR GFAFVEFYHL QDATSWMEAN QKKLVIQGKH IAMHYSNPRP
       190        200        210        220        230        240
KFEDWLCNKC CLNNFRKRLK CFRCGADKFD SEQEVPPGTT ESVQSVDYYC DTIILRNIAP
       250        260        270        280        290        300
HTVVDSIMTA LSPYASLAVN NIRLIKDKQT QQNRGFAFVQ LSSAMDASQL LQILQSLHPP
       310        320        330        340        350        360
LKIDGKTIGV DFAKSARKDL VLSDGNRVSA FSVASTAIAA AQWSSTQSQS GEGGSVDYSY
       370        380        390        400        410        420
LQPGQDGYAQ YAQYSQDYQQ FYQQQAGGLE SDASSASGTA VTTTSAAVVS QSPQLYNQTS
       430        440        450        460        470        480
NPPGSPTEEA QPSTSTSTQA PAASPTGVVP GTKYAVPDTS TYQYDESSGY YYDPTTGLYY
       490        500        510        520        530        540
DPNSQYYYNS LTQQYLYWDG EKETYVPAAE SSSHQQSGLP PAKEGKEKKE KPKSKTAQQI
       550        560        570        580        590        600
AKDMERWAKS LNKQKENFKN SFQPVNSLRE EERRESAAAD AGFALFEKKG ALAERQQLIP
       610        620        630        640        650        660
ELVRNGDEEN PLKRGLVAAY SGDSDNEEEL VERLESEEEK LADWKKMACL LCRRQFPNKD
       670        680        690        700        710        720
ALVRHQQLSD LHKQNMDIYR RSRLSEQELE ALELREREMK YRDRAAERRE KYGIPEPPEP
       730        740        750        760        770        780
KRKKQFDAGT VNYEQPTKDG IDHSNIGNKM LQAMGWREGS GLGRKCQGIT APIEAQVRLK
       790        800        810
GAGLGAKGSA YGLSGADSYK DAVRKAMFAR FTEME         10         20         30         40         50         60
MGSDKRVSRT ERSGRYGSII DRDDRDERES RSRRRDSDYK RSSDDRRGDR YDDYRDYDSP
        70         80         90        100        110        120
ERERERRNSD RSEDGYHSDG DYGEHDYRHD ISDERESKTI MLRGLPITIT ESDIREMMES
       130        140        150        160        170        180
FEGPQPADVR LMKRKTGVSR GFAFVEFYHL QDATSWMEAN QKKLVIQGKH IAMHYSNPRP
       190        200        210        220        230        240
KFEDWLCNKC CLNNFRKRLK CFRCGADKFD SEQEVPPGTT ESVQSVDYYC DTIILRNIAP
       250        260        270        280        290        300
HTVVDSIMTA LSPYASLAVN NIRLIKDKQT QQNRGFAFVQ LSSAMDASQL LQILQSLHPP
       310        320        330        340        350        360
LKIDGKTIGV DFAKSARKDL VLSDGNRVSA FSVASTAIAA AQWSSTQSQS GEGGSVDYSY
       370        380        390        400        410        420
LQPGQDGYAQ YAQYSQDYQQ FYQQQAGGLE SDASSASGTA VTTTSAAVVS QSPQLYNQTS
       430        440        450        460        470        480
NPPGSPTEEA QPSTSTSTQA PAASPTGVVP GTKYAVPDTS TYQYDESSGY YYDPTTGLYY
       490        500        510        520        530        540
DPNSQYYYNS LTQQYLYWDG EKETYVPAAE SSSHQQSGLP PAKEGKEKKE KPKSKTAQQI
       550        560        570        580        590        600
AKDMERWAKS LNKQKENFKN SFQPVNSLRE EERRESAAAD AGFALFEKKG ALAERQQLIP
       610        620        630        640        650        660
ELVRNGDEEN PLKRGLVAAY SGDSDNEEEL VERLESEEEK LADWKKMACL LCRRQFPNKD
       670        680        690        700        710        720
ALVRHQQLSD LHKQNMDIYR RSRLSEQELE ALELREREMK YRDRAAERRE KYGIPEPPEP
       730        740        750        760        770        780
KRKKQFDAGT VNYEQPTKDG IDHSNIGNKM LQAMGWREGS GLGRKCQGIT APIEAQVRLK
       790        800        810
GAGLGAKGSA YGLSGADSYK DAVRKAMFAR FTEME         10         20         30         40         50         60
MGSDKRVSRT ERSGRYGSII DRDDRDERES RSRRRDSDYK RSSDDRRGDR YDDYRDYDSP
        70         80         90        100        110        120
ERERERRNSD RSEDGYHSDG DYGEHDYRHD ISDERESKTI MLRGLPITIT ESDIREMMES
       130        140        150        160        170        180
FEGPQPADVR LMKRKTGVSR GFAFVEFYHL QDATSWMEAN QKKLVIQGKH IAMHYSNPRP
       190        200        210        220        230        240
KFEDWLCNKC CLNNFRKRLK CFRCGADKFD SEQEVPPGTT ESVQSVDYYC DTIILRNIAP
       250        260        270        280        290        300
HTVVDSIMTA LSPYASLAVN NIRLIKDKQT QQNRGFAFVQ LSSAMDASQL LQILQSLHPP
       310        320        330        340        350        360
LKIDGKTIGV DFAKSARKDL VLSDGNRVSA FSVASTAIAA AQWSSTQSQS GEGGSVDYSY
       370        380        390        400        410        420
LQPGQDGYAQ YAQYSQDYQQ FYQQQAGGLE SDASSASGTA VTTTSAAVVS QSPQLYNQTS
       430        440        450        460        470        480
NPPGSPTEEA QPSTSTSTQA PAASPTGVVP GTKYAVPDTS TYQYDESSGY YYDPTTGLYY
       490        500        510        520        530        540
DPNSQYYYNS LTQQYLYWDG EKETYVPAAE SSSHQQSGLP PAKEGKEKKE KPKSKTAQQI
       550        560        570        580        590        600
AKDMERWAKS LNKQKENFKN SFQPVNSLRE EERRESAAAD AGFALFEKKG ALAERQQLIP
       610        620        630        640        650        660
ELVRNGDEEN PLKRGLVAAY SGDSDNEEEL VERLESEEEK LADWKKMACL LCRRQFPNKD
       670        680        690        700        710        720
ALVRHQQLSD LHKQNMDIYR RSRLSEQELE ALELREREMK YRDRAAERRE KYGIPEPPEP
       730        740        750        760        770        780
KRKKQFDAGT VNYEQPTKDG IDHSNIGNKM LQAMGWREGS GLGRKCQGIT APIEAQVRLK
       790        800        810
GAGLGAKGSA YGLSGADSYK DAVRKAMFAR FTEME         10         20         30         40         50         60
MGSDKRVSRT ERSGRYGSII DRDDRDERES RSRRRDSDYK RSSDDRRGDR YDDYRDYDSP
        70         80         90        100        110        120
ERERERRNSD RSEDGYHSDG DYGEHDYRHD ISDERESKTI MLRGLPITIT ESDIREMMES
       130        140        150        160        170        180
FEGPQPADVR LMKRKTGVSR GFAFVEFYHL QDATSWMEAN QKKLVIQGKH IAMHYSNPRP
       190        200        210        220        230        240
KFEDWLCNKC CLNNFRKRLK CFRCGADKFD SEQEVPPGTT ESVQSVDYYC DTIILRNIAP
       250        260        270        280        290        300
HTVVDSIMTA LSPYASLAVN NIRLIKDKQT QQNRGFAFVQ LSSAMDASQL LQILQSLHPP
       310        320        330        340        350        360
LKIDGKTIGV DFAKSARKDL VLSDGNRVSA FSVASTAIAA AQWSSTQSQS GEGGSVDYSY
       370        380        390        400        410        420
LQPGQDGYAQ YAQYSQDYQQ FYQQQAGGLE SDASSASGTA VTTTSAAVVS QSPQLYNQTS
       430        440        450        460        470        480
NPPGSPTEEA QPSTSTSTQA PAASPTGVVP GTKYAVPDTS TYQYDESSGY YYDPTTGLYY
       490        500        510        520        530        540
DPNSQYYYNS LTQQYLYWDG EKETYVPAAE SSSHQQSGLP PAKEGKEKKE KPKSKTAQQI
       550        560        570        580        590        600
AKDMERWAKS LNKQKENFKN SFQPVNSLRE EERRESAAAD AGFALFEKKG ALAERQQLIP
       610        620        630        640        650        660
ELVRNGDEEN PLKRGLVAAY SGDSDNEEEL VERLESEEEK LADWKKMACL LCRRQFPNKD
       670        680        690        700        710        720
ALVRHQQLSD LHKQNMDIYR RSRLSEQELE ALELREREMK YRDRAAERRE KYGIPEPPEP
       730        740        750        760        770        780
KRKKQFDAGT VNYEQPTKDG IDHSNIGNKM LQAMGWREGS GLGRKCQGIT APIEAQVRLK
       790        800        810
GAGLGAKGSA YGLSGADSYK DAVRKAMFAR FTEME

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P52756-1-unknown	MGSDKR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P52756-1-unknown	MGSDKR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87146
P52756-1-unknown	MGSDKR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87147
P52756-1-unknown	MGSDKR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87148
P52756-1-unknown	MGSDKR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87149
P52756-104-unknown	GLPITI...	104	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176584
P52756-104-unknown	GLPITI...	104	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176585
P52756-104-unknown	GLPITI...	104	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176586
P52756-104-	GLPITI...	104		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P52756-104-	GLPITI...	104		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P52756-617-unknown	VAAYSG...	617	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14201

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GVSRGF	141	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82766
...LKRGLV	616	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14201
...FTEME	815	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	616	RGLV.\|.VAAY	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)