Q9NR56: Muscleblind-like protein 1

General Information

Protein names	- Muscleblind-like protein 1 - Triplet-expansion RNA-binding protein
Gene names	MBNL1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NR56

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Muscleblind-like protein 1 - Isoform 3 of Muscleblind-like protein 1 - Isoform 4 of Muscleblind-like protein 1 - Isoform 5 of Muscleblind-like protein 1 - Isoform 6 of Muscleblind-like protein 1 - Isoform 7 of Muscleblind-like protein 1

Sequence View

        10         20         30         40         50         60
MAVSVTPIRD TKWLTLEVCR EFQRGTCSRP DTECKFAHPS KSCQVENGRV IACFDSLKGR
        70         80         90        100        110        120
CSRENCKYLH PPPHLKTQLE INGRNNLIQQ KNMAMLAQQM QLANAMMPGA PLQPVPMFSV
       130        140        150        160        170        180
APSLATNASA AAFNPYLGPV SPSLVPAEIL PTAPMLVTGN PGVPVPAAAA AAAQKLMRTD
       190        200        210        220        230        240
RLEVCREYQR GNCNRGENDC RFAHPADSTM IDTNDNTVTV CMDYIKGRCS REKCKYFHPP
       250        260        270        280        290        300
AHLQAKIKAA QYQVNQAAAA QAAATAAAMT QSAVKSLKRP LEATFDLGIP QAVLPPLPKR
       310        320        330        340        350        360
PALEKTNGAT AVFNTGIFQY QQALANMQLQ QHTAFLPPVP MVHGATPATV SAATTSATSV
       370        380
PFAATATANQ IPIISAEHLT SHKYVTQM         10         20         30         40         50         60
MAVSVTPIRD TKWLTLEVCR EFQRGTCSRP DTECKFAHPS KSCQVENGRV IACFDSLKGR
        70         80         90        100        110        120
CSRENCKYLH PPPHLKTQLE INGRNNLIQQ KNMAMLAQQM QLANAMMPGA PLQPVPMFSV
       130        140        150        160        170        180
APSLATNASA AAFNPYLGPV SPSLVPAEIL PTAPMLVTGN PGVPVPAAAA AAAQKLMRTD
       190        200        210        220        230        240
RLEVCREYQR GNCNRGENDC RFAHPADSTM IDTNDNTVTV CMDYIKGRCS REKCKYFHPP
       250        260        270        280        290        300
AHLQAKIKAA QYQVNQAAAA QAAATAAAMT QSAVKSLKRP LEATFDLGIP QAVLPPLPKR
       310        320        330        340        350        360
PALEKTNGAT AVFNTGIFQY QQALANMQLQ QHTAFLPPVP MVHGATPATV SAATTSATSV
       370        380
PFAATATANQ IPIISAEHLT SHKYVTQM         10         20         30         40         50         60
MAVSVTPIRD TKWLTLEVCR EFQRGTCSRP DTECKFAHPS KSCQVENGRV IACFDSLKGR
        70         80         90        100        110        120
CSRENCKYLH PPPHLKTQLE INGRNNLIQQ KNMAMLAQQM QLANAMMPGA PLQPVPMFSV
       130        140        150        160        170        180
APSLATNASA AAFNPYLGPV SPSLVPAEIL PTAPMLVTGN PGVPVPAAAA AAAQKLMRTD
       190        200        210        220        230        240
RLEVCREYQR GNCNRGENDC RFAHPADSTM IDTNDNTVTV CMDYIKGRCS REKCKYFHPP
       250        260        270        280        290        300
AHLQAKIKAA QYQVNQAAAA QAAATAAAMT QSAVKSLKRP LEATFDLGIP QAVLPPLPKR
       310        320        330        340        350        360
PALEKTNGAT AVFNTGIFQY QQALANMQLQ QHTAFLPPVP MVHGATPATV SAATTSATSV
       370        380
PFAATATANQ IPIISAEHLT SHKYVTQM         10         20         30         40         50         60
MAVSVTPIRD TKWLTLEVCR EFQRGTCSRP DTECKFAHPS KSCQVENGRV IACFDSLKGR
        70         80         90        100        110        120
CSRENCKYLH PPPHLKTQLE INGRNNLIQQ KNMAMLAQQM QLANAMMPGA PLQPVPMFSV
       130        140        150        160        170        180
APSLATNASA AAFNPYLGPV SPSLVPAEIL PTAPMLVTGN PGVPVPAAAA AAAQKLMRTD
       190        200        210        220        230        240
RLEVCREYQR GNCNRGENDC RFAHPADSTM IDTNDNTVTV CMDYIKGRCS REKCKYFHPP
       250        260        270        280        290        300
AHLQAKIKAA QYQVNQAAAA QAAATAAAMT QSAVKSLKRP LEATFDLGIP QAVLPPLPKR
       310        320        330        340        350        360
PALEKTNGAT AVFNTGIFQY QQALANMQLQ QHTAFLPPVP MVHGATPATV SAATTSATSV
       370        380
PFAATATANQ IPIISAEHLT SHKYVTQM         10         20         30         40         50         60
MAVSVTPIRD TKWLTLEVCR EFQRGTCSRP DTECKFAHPS KSCQVENGRV IACFDSLKGR
        70         80         90        100        110        120
CSRENCKYLH PPPHLKTQLE INGRNNLIQQ KNMAMLAQQM QLANAMMPGA PLQPVPMFSV
       130        140        150        160        170        180
APSLATNASA AAFNPYLGPV SPSLVPAEIL PTAPMLVTGN PGVPVPAAAA AAAQKLMRTD
       190        200        210        220        230        240
RLEVCREYQR GNCNRGENDC RFAHPADSTM IDTNDNTVTV CMDYIKGRCS REKCKYFHPP
       250        260        270        280        290        300
AHLQAKIKAA QYQVNQAAAA QAAATAAAMT QSAVKSLKRP LEATFDLGIP QAVLPPLPKR
       310        320        330        340        350        360
PALEKTNGAT AVFNTGIFQY QQALANMQLQ QHTAFLPPVP MVHGATPATV SAATTSATSV
       370        380
PFAATATANQ IPIISAEHLT SHKYVTQM         10         20         30         40         50         60
MAVSVTPIRD TKWLTLEVCR EFQRGTCSRP DTECKFAHPS KSCQVENGRV IACFDSLKGR
        70         80         90        100        110        120
CSRENCKYLH PPPHLKTQLE INGRNNLIQQ KNMAMLAQQM QLANAMMPGA PLQPVPMFSV
       130        140        150        160        170        180
APSLATNASA AAFNPYLGPV SPSLVPAEIL PTAPMLVTGN PGVPVPAAAA AAAQKLMRTD
       190        200        210        220        230        240
RLEVCREYQR GNCNRGENDC RFAHPADSTM IDTNDNTVTV CMDYIKGRCS REKCKYFHPP
       250        260        270        280        290        300
AHLQAKIKAA QYQVNQAAAA QAAATAAAMT QSAVKSLKRP LEATFDLGIP QAVLPPLPKR
       310        320        330        340        350        360
PALEKTNGAT AVFNTGIFQY QQALANMQLQ QHTAFLPPVP MVHGATPATV SAATTSATSV
       370        380
PFAATATANQ IPIISAEHLT SHKYVTQM

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NR56-1-unknown	MAVSVT...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NR56-1-unknown	MAVSVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt80537
Q9NR56-1-unknown	MAVSVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt80538
Q9NR56-1-unknown	MAVSVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt80539
Q9NR56-1-unknown	MAVSVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt80540
Q9NR56-1-unknown	MAVSVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt80541
Q9NR56-1-unknown	MAVSVT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt80542
Q9NR56-2-acetylation	AVSVTP...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9NR56-2-acetylation	AVSVTP...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9NR56-2-acetylation	AVSVTP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162749
Q9NR56-2-acetylation	AVSVTP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162750
Q9NR56-2-acetylation	AVSVTP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162751
Q9NR56-2-acetylation	AVSVTP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162752
Q9NR56-2-acetylation	AVSVTP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162753
Q9NR56-2-acetylation	AVSVTP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162754
Q9NR56-168-unknown	AAAAAA...	168		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15025
Q9NR56-168-unknown	AAAAAA...	168		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145462
Q9NR56-168-unknown	AAAAAA...	168		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145463
Q9NR56-168-unknown	AAAAAA...	168		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145464
Q9NR56-168-unknown	AAAAAA...	168		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145465

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VPVPAA	167	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15025
...VPVPAA	167	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128757
...VPVPAA	167	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128758
...VPVPAA	167	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128759
...VPVPAA	167	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt128760
...YVTQM	388	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...YVTQM	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76156
...YVTQM	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76157
...YVTQM	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76155
...YVTQM	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76158

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	167	VPAA.\|.AAAA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)