Q969X1: Protein lifeguard 3

General Information

Protein names	- Protein lifeguard 3 - Protein RECS1 homolog - Transmembrane BAX inhibitor motif-containing protein 1
Gene names	TMBIM1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q969X1

5 N-termini

13 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSNPSAPPPY EDRNPLYPGP PPPGGYGQPS VLPGGYPAYP GYPQPGYGHP AGYPQPMPPT
        70         80         90        100        110        120
HPMPMNYGPG HGYDGEERAV SDSFGPGEWD DRKVRHTFIR KVYSIISVQL LITVAIIAIF
       130        140        150        160        170        180
TFVEPVSAFV RRNVAVYYVS YAVFVVTYLI LACCQGPRRR FPWNIILLTL FTFAMGFMTG
       190        200        210        220        230        240
TISSMYQTKA VIIAMIITAV VSISVTIFCF QTKVDFTSCT GLFCVLGIVL LVTGIVTSIV
       250        260        270        280        290        300
LYFQYVYWLH MLYAALGAIC FTLFLAYDTQ LVLGNRKHTI SPEDYITGAL QIYTDIIYIF
       310
TFVLQLMGDR N

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 13 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
Q969X1-1-unknown	MSNPSA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q969X1-2-acetylation	SNPSAP...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q969X1-66-unknown	NYGPGH...	66		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14821
Q969X1-67-	YGPGHG...	67			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q969X1-175-unknown	MGFMTG...	175		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000401491

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YPQPGY	46	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000408729
...HPMPMN	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14821
...MPMNYG	67	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000405516
...PGHGYD	73	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394946
...VSDSFG	84	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000395614
...PGEWDD	90	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000403462
...GEWDDR	91	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000410771
...VYSIIS	106	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000410136
...YSIISV	107	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000412518
...VTYLIL	150	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000406744
...WNIILL	167	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399345
...LLTLFT	171	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399987
...MGDRN	311	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	65	MPMN.\|.NYGP	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)