Q13574: Diacylglycerol kinase zeta

General Information

Protein names	- Diacylglycerol kinase zeta - DAG kinase zeta - 2.7.1.107 - Diglyceride kinase zeta - DGK-zeta
Gene names	DGKZ
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13574

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Diacylglycerol kinase zeta - Isoform 3 of Diacylglycerol kinase zeta - Isoform 4 of Diacylglycerol kinase zeta - Isoform 5 of Diacylglycerol kinase zeta - Isoform 6 of Diacylglycerol kinase zeta - Isoform 7 of Diacylglycerol kinase zeta

Sequence View

        10         20         30         40         50         60
METFFRRHFR GKVPGPGEGQ QRPSSVGLPT GKARRRSPAG QASSSLAQRR RSSAQLQGCL
        70         80         90        100        110        120
LSCGVRAQGS SRRRSSTVPP SCNPRFIVDK VLTPQPTTVG AQLLGAPLLL TGLVGMNEEE
       130        140        150        160        170        180
GVQEDVVAEA SSAIQPGTKT PGPPPPRGAQ PLLPLPRYLR RASSHLLPAD AVYDHALWGL
       190        200        210        220        230        240
HGYYRRLSQR RPSGQHPGPG GRRASGTTAG TMLPTRVRPL SRRRQVALRR KAAGPQAWSA
       250        260        270        280        290        300
LLAKAITKSG LQHLAPPPPT PGAPCSESER QIRSTVDWSE SATYGEHIWF ETNVSGDFCY
       310        320        330        340        350        360
VGEQYCVARM LKSVSRRKCA ACKIVVHTPC IEQLEKINFR CKPSFRESGS RNVREPTFVR
       370        380        390        400        410        420
HHWVHRRRQD GKCRHCGKGF QQKFTFHSKE IVAISCSWCK QAYHSKVSCF MLQQIEEPCS
       430        440        450        460        470        480
LGVHAAVVIP PTWILRARRP QNTLKASKKK KRASFKRKSS KKGPEEGRWR PFIIRPTPSP
       490        500        510        520        530        540
LMKPLLVFVN PKSGGNQGAK IIQSFLWYLN PRQVFDLSQG GPKEALEMYR KVHNLRILAC
       550        560        570        580        590        600
GGDGTVGWIL STLDQLRLKP PPPVAILPLG TGNDLARTLN WGGGYTDEPV SKILSHVEEG
       610        620        630        640        650        660
NVVQLDRWDL HAEPNPEAGP EDRDEGATDR LPLDVFNNYF SLGFDAHVTL EFHESREANP
       670        680        690        700        710        720
EKFNSRFRNK MFYAGTAFSD FLMGSSKDLA KHIRVVCDGM DLTPKIQDLK PQCVVFLNIP
       730        740        750        760        770        780
RYCAGTMPWG HPGEHHDFEP QRHDDGYLEV IGFTMTSLAA LQVGGHGERL TQCREVVLTT
       790        800        810        820        830        840
SKAIPVQVDG EPCKLAASRI RIALRNQATM VQKAKRRSAA PLHSDQQPVP EQLRIQVSRV
       850        860        870        880        890        900
SMHDYEALHY DKEQLKEASV PLGTVVVPGD SDLELCRAHI ERLQQEPDGA GAKSPTCQKL
       910        920        930        940        950        960
SPKWCFLDAT TASRFYRIDR AQEHLNYVTE IAQDEIYILD PELLGASARP DLPTPTSPLP
       970        980        990       1000       1010       1020
TSPCSPTPRS LQGDAAPPQG EELIEAAKRN DFCKLQELHR AGGDLMHRDE QSRTLLHHAV
      1030       1040       1050       1060       1070       1080
STGSKDVVRY LLDHAPPEIL DAVEENGETC LHQAAALGQR TICHYIVEAG ASLMKTDQQG
      1090       1100       1110
DTPRQRAEKA QDTELAAYLE NRQHYQMIQR EDQETAV         10         20         30         40         50         60
METFFRRHFR GKVPGPGEGQ QRPSSVGLPT GKARRRSPAG QASSSLAQRR RSSAQLQGCL
        70         80         90        100        110        120
LSCGVRAQGS SRRRSSTVPP SCNPRFIVDK VLTPQPTTVG AQLLGAPLLL TGLVGMNEEE
       130        140        150        160        170        180
GVQEDVVAEA SSAIQPGTKT PGPPPPRGAQ PLLPLPRYLR RASSHLLPAD AVYDHALWGL
       190        200        210        220        230        240
HGYYRRLSQR RPSGQHPGPG GRRASGTTAG TMLPTRVRPL SRRRQVALRR KAAGPQAWSA
       250        260        270        280        290        300
LLAKAITKSG LQHLAPPPPT PGAPCSESER QIRSTVDWSE SATYGEHIWF ETNVSGDFCY
       310        320        330        340        350        360
VGEQYCVARM LKSVSRRKCA ACKIVVHTPC IEQLEKINFR CKPSFRESGS RNVREPTFVR
       370        380        390        400        410        420
HHWVHRRRQD GKCRHCGKGF QQKFTFHSKE IVAISCSWCK QAYHSKVSCF MLQQIEEPCS
       430        440        450        460        470        480
LGVHAAVVIP PTWILRARRP QNTLKASKKK KRASFKRKSS KKGPEEGRWR PFIIRPTPSP
       490        500        510        520        530        540
LMKPLLVFVN PKSGGNQGAK IIQSFLWYLN PRQVFDLSQG GPKEALEMYR KVHNLRILAC
       550        560        570        580        590        600
GGDGTVGWIL STLDQLRLKP PPPVAILPLG TGNDLARTLN WGGGYTDEPV SKILSHVEEG
       610        620        630        640        650        660
NVVQLDRWDL HAEPNPEAGP EDRDEGATDR LPLDVFNNYF SLGFDAHVTL EFHESREANP
       670        680        690        700        710        720
EKFNSRFRNK MFYAGTAFSD FLMGSSKDLA KHIRVVCDGM DLTPKIQDLK PQCVVFLNIP
       730        740        750        760        770        780
RYCAGTMPWG HPGEHHDFEP QRHDDGYLEV IGFTMTSLAA LQVGGHGERL TQCREVVLTT
       790        800        810        820        830        840
SKAIPVQVDG EPCKLAASRI RIALRNQATM VQKAKRRSAA PLHSDQQPVP EQLRIQVSRV
       850        860        870        880        890        900
SMHDYEALHY DKEQLKEASV PLGTVVVPGD SDLELCRAHI ERLQQEPDGA GAKSPTCQKL
       910        920        930        940        950        960
SPKWCFLDAT TASRFYRIDR AQEHLNYVTE IAQDEIYILD PELLGASARP DLPTPTSPLP
       970        980        990       1000       1010       1020
TSPCSPTPRS LQGDAAPPQG EELIEAAKRN DFCKLQELHR AGGDLMHRDE QSRTLLHHAV
      1030       1040       1050       1060       1070       1080
STGSKDVVRY LLDHAPPEIL DAVEENGETC LHQAAALGQR TICHYIVEAG ASLMKTDQQG
      1090       1100       1110
DTPRQRAEKA QDTELAAYLE NRQHYQMIQR EDQETAV         10         20         30         40         50         60
METFFRRHFR GKVPGPGEGQ QRPSSVGLPT GKARRRSPAG QASSSLAQRR RSSAQLQGCL
        70         80         90        100        110        120
LSCGVRAQGS SRRRSSTVPP SCNPRFIVDK VLTPQPTTVG AQLLGAPLLL TGLVGMNEEE
       130        140        150        160        170        180
GVQEDVVAEA SSAIQPGTKT PGPPPPRGAQ PLLPLPRYLR RASSHLLPAD AVYDHALWGL
       190        200        210        220        230        240
HGYYRRLSQR RPSGQHPGPG GRRASGTTAG TMLPTRVRPL SRRRQVALRR KAAGPQAWSA
       250        260        270        280        290        300
LLAKAITKSG LQHLAPPPPT PGAPCSESER QIRSTVDWSE SATYGEHIWF ETNVSGDFCY
       310        320        330        340        350        360
VGEQYCVARM LKSVSRRKCA ACKIVVHTPC IEQLEKINFR CKPSFRESGS RNVREPTFVR
       370        380        390        400        410        420
HHWVHRRRQD GKCRHCGKGF QQKFTFHSKE IVAISCSWCK QAYHSKVSCF MLQQIEEPCS
       430        440        450        460        470        480
LGVHAAVVIP PTWILRARRP QNTLKASKKK KRASFKRKSS KKGPEEGRWR PFIIRPTPSP
       490        500        510        520        530        540
LMKPLLVFVN PKSGGNQGAK IIQSFLWYLN PRQVFDLSQG GPKEALEMYR KVHNLRILAC
       550        560        570        580        590        600
GGDGTVGWIL STLDQLRLKP PPPVAILPLG TGNDLARTLN WGGGYTDEPV SKILSHVEEG
       610        620        630        640        650        660
NVVQLDRWDL HAEPNPEAGP EDRDEGATDR LPLDVFNNYF SLGFDAHVTL EFHESREANP
       670        680        690        700        710        720
EKFNSRFRNK MFYAGTAFSD FLMGSSKDLA KHIRVVCDGM DLTPKIQDLK PQCVVFLNIP
       730        740        750        760        770        780
RYCAGTMPWG HPGEHHDFEP QRHDDGYLEV IGFTMTSLAA LQVGGHGERL TQCREVVLTT
       790        800        810        820        830        840
SKAIPVQVDG EPCKLAASRI RIALRNQATM VQKAKRRSAA PLHSDQQPVP EQLRIQVSRV
       850        860        870        880        890        900
SMHDYEALHY DKEQLKEASV PLGTVVVPGD SDLELCRAHI ERLQQEPDGA GAKSPTCQKL
       910        920        930        940        950        960
SPKWCFLDAT TASRFYRIDR AQEHLNYVTE IAQDEIYILD PELLGASARP DLPTPTSPLP
       970        980        990       1000       1010       1020
TSPCSPTPRS LQGDAAPPQG EELIEAAKRN DFCKLQELHR AGGDLMHRDE QSRTLLHHAV
      1030       1040       1050       1060       1070       1080
STGSKDVVRY LLDHAPPEIL DAVEENGETC LHQAAALGQR TICHYIVEAG ASLMKTDQQG
      1090       1100       1110
DTPRQRAEKA QDTELAAYLE NRQHYQMIQR EDQETAV         10         20         30         40         50         60
METFFRRHFR GKVPGPGEGQ QRPSSVGLPT GKARRRSPAG QASSSLAQRR RSSAQLQGCL
        70         80         90        100        110        120
LSCGVRAQGS SRRRSSTVPP SCNPRFIVDK VLTPQPTTVG AQLLGAPLLL TGLVGMNEEE
       130        140        150        160        170        180
GVQEDVVAEA SSAIQPGTKT PGPPPPRGAQ PLLPLPRYLR RASSHLLPAD AVYDHALWGL
       190        200        210        220        230        240
HGYYRRLSQR RPSGQHPGPG GRRASGTTAG TMLPTRVRPL SRRRQVALRR KAAGPQAWSA
       250        260        270        280        290        300
LLAKAITKSG LQHLAPPPPT PGAPCSESER QIRSTVDWSE SATYGEHIWF ETNVSGDFCY
       310        320        330        340        350        360
VGEQYCVARM LKSVSRRKCA ACKIVVHTPC IEQLEKINFR CKPSFRESGS RNVREPTFVR
       370        380        390        400        410        420
HHWVHRRRQD GKCRHCGKGF QQKFTFHSKE IVAISCSWCK QAYHSKVSCF MLQQIEEPCS
       430        440        450        460        470        480
LGVHAAVVIP PTWILRARRP QNTLKASKKK KRASFKRKSS KKGPEEGRWR PFIIRPTPSP
       490        500        510        520        530        540
LMKPLLVFVN PKSGGNQGAK IIQSFLWYLN PRQVFDLSQG GPKEALEMYR KVHNLRILAC
       550        560        570        580        590        600
GGDGTVGWIL STLDQLRLKP PPPVAILPLG TGNDLARTLN WGGGYTDEPV SKILSHVEEG
       610        620        630        640        650        660
NVVQLDRWDL HAEPNPEAGP EDRDEGATDR LPLDVFNNYF SLGFDAHVTL EFHESREANP
       670        680        690        700        710        720
EKFNSRFRNK MFYAGTAFSD FLMGSSKDLA KHIRVVCDGM DLTPKIQDLK PQCVVFLNIP
       730        740        750        760        770        780
RYCAGTMPWG HPGEHHDFEP QRHDDGYLEV IGFTMTSLAA LQVGGHGERL TQCREVVLTT
       790        800        810        820        830        840
SKAIPVQVDG EPCKLAASRI RIALRNQATM VQKAKRRSAA PLHSDQQPVP EQLRIQVSRV
       850        860        870        880        890        900
SMHDYEALHY DKEQLKEASV PLGTVVVPGD SDLELCRAHI ERLQQEPDGA GAKSPTCQKL
       910        920        930        940        950        960
SPKWCFLDAT TASRFYRIDR AQEHLNYVTE IAQDEIYILD PELLGASARP DLPTPTSPLP
       970        980        990       1000       1010       1020
TSPCSPTPRS LQGDAAPPQG EELIEAAKRN DFCKLQELHR AGGDLMHRDE QSRTLLHHAV
      1030       1040       1050       1060       1070       1080
STGSKDVVRY LLDHAPPEIL DAVEENGETC LHQAAALGQR TICHYIVEAG ASLMKTDQQG
      1090       1100       1110
DTPRQRAEKA QDTELAAYLE NRQHYQMIQR EDQETAV         10         20         30         40         50         60
METFFRRHFR GKVPGPGEGQ QRPSSVGLPT GKARRRSPAG QASSSLAQRR RSSAQLQGCL
        70         80         90        100        110        120
LSCGVRAQGS SRRRSSTVPP SCNPRFIVDK VLTPQPTTVG AQLLGAPLLL TGLVGMNEEE
       130        140        150        160        170        180
GVQEDVVAEA SSAIQPGTKT PGPPPPRGAQ PLLPLPRYLR RASSHLLPAD AVYDHALWGL
       190        200        210        220        230        240
HGYYRRLSQR RPSGQHPGPG GRRASGTTAG TMLPTRVRPL SRRRQVALRR KAAGPQAWSA
       250        260        270        280        290        300
LLAKAITKSG LQHLAPPPPT PGAPCSESER QIRSTVDWSE SATYGEHIWF ETNVSGDFCY
       310        320        330        340        350        360
VGEQYCVARM LKSVSRRKCA ACKIVVHTPC IEQLEKINFR CKPSFRESGS RNVREPTFVR
       370        380        390        400        410        420
HHWVHRRRQD GKCRHCGKGF QQKFTFHSKE IVAISCSWCK QAYHSKVSCF MLQQIEEPCS
       430        440        450        460        470        480
LGVHAAVVIP PTWILRARRP QNTLKASKKK KRASFKRKSS KKGPEEGRWR PFIIRPTPSP
       490        500        510        520        530        540
LMKPLLVFVN PKSGGNQGAK IIQSFLWYLN PRQVFDLSQG GPKEALEMYR KVHNLRILAC
       550        560        570        580        590        600
GGDGTVGWIL STLDQLRLKP PPPVAILPLG TGNDLARTLN WGGGYTDEPV SKILSHVEEG
       610        620        630        640        650        660
NVVQLDRWDL HAEPNPEAGP EDRDEGATDR LPLDVFNNYF SLGFDAHVTL EFHESREANP
       670        680        690        700        710        720
EKFNSRFRNK MFYAGTAFSD FLMGSSKDLA KHIRVVCDGM DLTPKIQDLK PQCVVFLNIP
       730        740        750        760        770        780
RYCAGTMPWG HPGEHHDFEP QRHDDGYLEV IGFTMTSLAA LQVGGHGERL TQCREVVLTT
       790        800        810        820        830        840
SKAIPVQVDG EPCKLAASRI RIALRNQATM VQKAKRRSAA PLHSDQQPVP EQLRIQVSRV
       850        860        870        880        890        900
SMHDYEALHY DKEQLKEASV PLGTVVVPGD SDLELCRAHI ERLQQEPDGA GAKSPTCQKL
       910        920        930        940        950        960
SPKWCFLDAT TASRFYRIDR AQEHLNYVTE IAQDEIYILD PELLGASARP DLPTPTSPLP
       970        980        990       1000       1010       1020
TSPCSPTPRS LQGDAAPPQG EELIEAAKRN DFCKLQELHR AGGDLMHRDE QSRTLLHHAV
      1030       1040       1050       1060       1070       1080
STGSKDVVRY LLDHAPPEIL DAVEENGETC LHQAAALGQR TICHYIVEAG ASLMKTDQQG
      1090       1100       1110
DTPRQRAEKA QDTELAAYLE NRQHYQMIQR EDQETAV         10         20         30         40         50         60
METFFRRHFR GKVPGPGEGQ QRPSSVGLPT GKARRRSPAG QASSSLAQRR RSSAQLQGCL
        70         80         90        100        110        120
LSCGVRAQGS SRRRSSTVPP SCNPRFIVDK VLTPQPTTVG AQLLGAPLLL TGLVGMNEEE
       130        140        150        160        170        180
GVQEDVVAEA SSAIQPGTKT PGPPPPRGAQ PLLPLPRYLR RASSHLLPAD AVYDHALWGL
       190        200        210        220        230        240
HGYYRRLSQR RPSGQHPGPG GRRASGTTAG TMLPTRVRPL SRRRQVALRR KAAGPQAWSA
       250        260        270        280        290        300
LLAKAITKSG LQHLAPPPPT PGAPCSESER QIRSTVDWSE SATYGEHIWF ETNVSGDFCY
       310        320        330        340        350        360
VGEQYCVARM LKSVSRRKCA ACKIVVHTPC IEQLEKINFR CKPSFRESGS RNVREPTFVR
       370        380        390        400        410        420
HHWVHRRRQD GKCRHCGKGF QQKFTFHSKE IVAISCSWCK QAYHSKVSCF MLQQIEEPCS
       430        440        450        460        470        480
LGVHAAVVIP PTWILRARRP QNTLKASKKK KRASFKRKSS KKGPEEGRWR PFIIRPTPSP
       490        500        510        520        530        540
LMKPLLVFVN PKSGGNQGAK IIQSFLWYLN PRQVFDLSQG GPKEALEMYR KVHNLRILAC
       550        560        570        580        590        600
GGDGTVGWIL STLDQLRLKP PPPVAILPLG TGNDLARTLN WGGGYTDEPV SKILSHVEEG
       610        620        630        640        650        660
NVVQLDRWDL HAEPNPEAGP EDRDEGATDR LPLDVFNNYF SLGFDAHVTL EFHESREANP
       670        680        690        700        710        720
EKFNSRFRNK MFYAGTAFSD FLMGSSKDLA KHIRVVCDGM DLTPKIQDLK PQCVVFLNIP
       730        740        750        760        770        780
RYCAGTMPWG HPGEHHDFEP QRHDDGYLEV IGFTMTSLAA LQVGGHGERL TQCREVVLTT
       790        800        810        820        830        840
SKAIPVQVDG EPCKLAASRI RIALRNQATM VQKAKRRSAA PLHSDQQPVP EQLRIQVSRV
       850        860        870        880        890        900
SMHDYEALHY DKEQLKEASV PLGTVVVPGD SDLELCRAHI ERLQQEPDGA GAKSPTCQKL
       910        920        930        940        950        960
SPKWCFLDAT TASRFYRIDR AQEHLNYVTE IAQDEIYILD PELLGASARP DLPTPTSPLP
       970        980        990       1000       1010       1020
TSPCSPTPRS LQGDAAPPQG EELIEAAKRN DFCKLQELHR AGGDLMHRDE QSRTLLHHAV
      1030       1040       1050       1060       1070       1080
STGSKDVVRY LLDHAPPEIL DAVEENGETC LHQAAALGQR TICHYIVEAG ASLMKTDQQG
      1090       1100       1110
DTPRQRAEKA QDTELAAYLE NRQHYQMIQR EDQETAV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13574-1-unknown	METFFR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13574-445-unknown	KASKKK...	445	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14442
Q13574-445-unknown	KASKKK...	445	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147877
Q13574-445-unknown	KASKKK...	445	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148684
Q13574-445-unknown	KASKKK...	445	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148713
Q13574-445-unknown	KASKKK...	445	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148714
Q13574-445-unknown	KASKKK...	445	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149192
Q13574-818-unknown	SAAPLH...	818	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174317
Q13574-818-unknown	SAAPLH...	818	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174321
Q13574-818-unknown	SAAPLH...	818	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174318
Q13574-818-unknown	SAAPLH...	818	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174319
Q13574-818-unknown	SAAPLH...	818	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174320
Q13574-818-	SAAPLH...	818		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13574-818-	SAAPLH...	818		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q13574-823-unknown	HSDQQP...	823	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14448
Q13574-823-unknown	HSDQQP...	823	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt154775
Q13574-823-unknown	HSDQQP...	823	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155121
Q13574-823-unknown	HSDQQP...	823	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155132
Q13574-823-unknown	HSDQQP...	823	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155133
Q13574-823-unknown	HSDQQP...	823	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt155329

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PQNTLK	444	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14442
...PQNTLK	444	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131235
...PQNTLK	444	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132059
...PQNTLK	444	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132088
...PQNTLK	444	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132089
...PQNTLK	444	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132577
...SAAPLH	822	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14448
...SAAPLH	822	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt138201
...SAAPLH	822	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt138548
...SAAPLH	822	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt138560
...SAAPLH	822	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt138561
...SAAPLH	822	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt138762
...QETAV	1117	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QETAV	1117	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68303
...QETAV	1117	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68299
...QETAV	1117	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68301
...QETAV	1117	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68302
...QETAV	1117	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68300

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	444	NTLK.\|.KASK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	822	APLH.\|.HSDQ	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)