Q03111: Protein ENL

General Information

Protein names	- Protein ENL - YEATS domain-containing protein 1
Gene names	MLLT1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q03111

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDNQCTVQVR LELGHRAQLR KKPTTEGFTH DWMVFVRGPE QCDIQHFVEK VVFWLHDSFP
        70         80         90        100        110        120
KPRRVCKEPP YKVEESGYAG FIMPIEVHFK NKEEPRKVCF TYDLFLNLEG NPPVNHLRCE
       130        140        150        160        170        180
KLTFNNPTTE FRYKLLRAGG VMVMPEGADT VSRPSPDYPM LPTIPLSAFS DPKKTKPSHG
       190        200        210        220        230        240
SKDANKESSK TSKPHKVTKE HRERPRKDSE SKSSSKELER EQAKSSKDTS RKLGEGRLPK
       250        260        270        280        290        300
EEKAPPPKAA FKEPKMALKE TKLESTSPKG GPPPPPPPPP RASSKRPATA DSPKPSAKKQ
       310        320        330        340        350        360
KKSSSKGSRS APGTSPRTSS SSSFSDKKPA KDKSSTRGEK VKAESEPREA KKALEVEESN
       370        380        390        400        410        420
SEDEASFKSE SAQSSPSNSS SSSDSSSDSD FEPSQNHSQG PLRSMVEDLQ SEESDEDDSS
       430        440        450        460        470        480
SGEEAAGKTN PGRDSRLSFS DSESDNSADS SLPSREPPPP QKPPPPNSKV SGRRSPESCS
       490        500        510        520        530        540
KPEKILKKGT YDKAYTDELV ELHRRLMALR ERNVLQQIVN LIEETGHFNV TNTTFDFDLF
       550
SLDETTVRKL QSCLEAVAT

Isoforms

Sequence View

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Evidence Codes:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q03111-1-Acetylation	MDNQCT...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q03111-1-Acetylation	MDNQCT...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q03111-1-Acetylation	MDNQCT...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q03111-160-	MLPTIP...	160			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q03111-160-	MLPTIP...	160			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q03111-289-unknown	TADSPK...	289		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14369

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...SKRPAT	288	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14369
...EAVAT	559	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...EAVAT	559		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...EAVAT	559		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...EAVAT	559		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...EAVAT	559		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	288	RPAT.\|.TADS	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)