D3Z6P0: Protein disulfide-isomerase A2 {ECO:0000250|UniProtKB:Q13087}

General Information

Protein names	- Protein disulfide-isomerase A2 {ECO:0000250\|UniProtKB:Q13087} - 5.3.4.1 - PDIp {ECO:0000250\|UniProtKB:Q13087}
Gene names	Pdia2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	D3Z6P0

3 N-termini

2 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDKQLLPVLL LLLGVSGSWG QGEEPGGPSE VLPEEPTGEE VPKEDGILVL NHRTLSLALQ
        70         80         90        100        110        120
EHSALMVEFY APWCGHCKEL APEYSKAAAL LAAESAVVTL AKVDGPAEPE LTKEFEVVGY
       130        140        150        160        170        180
PTLKFFQNGN RTNPEEYAGP KTAEGIAEWL RRRVGPSATH LEDEEGVQAL MAKWDMVVIG
       190        200        210        220        230        240
FFQDLQGKDM ATFLALAKDA LDMTFGFTDQ PQLFEKFGLT KDTVVLFKKF DEGRADFPVD
       250        260        270        280        290        300
KETGLDLGDL SRFLVIHSMH LVTEFNSQTS PKIFAAKILN HLLLFVNQTL AQHRELLTDF
       310        320        330        340        350        360
REAAPPFRGQ VLFVMVDVAA DNSHVLNYFG LKAEEAPTLR LINVETTKKY APTGVIAITA
       370        380        390        400        410        420
ASVAAFCQAV LHGEIKHYLL SQEIPPDWDQ GPVKTLVSKN FEQVAFDETK NVFVKFYAPW
       430        440        450        460        470        480
CSHCKEMAPA WEALAEKYKD REDIVIAELD ATANELEAFS VLGYPTLKFF PAGPDRKVID
       490        500        510        520
YKSTRDLETF SKFLDSGGHL PKEEPKEPAA SAPEAQANST LGPKEEL

Isoforms

- Isoform 2 of Protein disulfide-isomerase A2

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
D3Z6P0-1-unknown	MDKQLL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84743
D3Z6P0-21-unknown	QGEEPG...	21	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
D3Z6P0-21-unknown	QGEEPG...	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112634
D3Z6P0-227-unknown	FKKFDE...	227	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29467
D3Z6P0-227-unknown	FKKFDE...	227	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28628
D3Z6P0-227-unknown	FKKFDE...	227	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt147505

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DTVVLF	226	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29467
...DTVVLF	226	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28628
...DTVVLF	226	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130855
...PKEEL	527	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PKEEL	527	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80361

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	226	VVLF.\|.FKKF	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PDIA2_MOUSE @226
CATD_MOUSE	226	VVLF.\|.FKKF	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)