O08665: Semaphorin-3A

General Information

Protein names	- Semaphorin-3A - Semaphorin III - Sema III - Semaphorin-D - Sema D
Gene names	Sema3a
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O08665

3 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGWFTGIACL FWGVLLTARA NYANGKNNVP RLKLSYKEML ESNNVITFNG LANSSSYHTF
        70         80         90        100        110        120
LLDEERSRLY VGAKDHIFSF NLVNIKDFQK IVWPVSYTRR DECKWAGKDI LKECANFIKV
       130        140        150        160        170        180
LEAYNQTHLY ACGTGAFHPI CTYIEVGHHP EDNIFKLQDS HFENGRGKSP YDPKLLTASL
       190        200        210        220        230        240
LIDGELYSGT AADFMGRDFA IFRTLGHHHP IRTEQHDSRW LNDPRFISAH LIPESDNPED
       250        260        270        280        290        300
DKVYFFFREN AIDGEHSGKA THARIGQICK NDFGGHRSLV NKWTTFLKAR LICSVPGPNG
       310        320        330        340        350        360
IDTHFDELQD VFLMNSKDPK NPIVYGVFTT SSNIFKGSAV CMYSMSDVRR VFLGPYAHRD
       370        380        390        400        410        420
GPNYQWVPYQ GRVPYPRPGT CPSKTFGGFD STKDLPDDVI TFARSHPAMY NPVFPINNRP
       430        440        450        460        470        480
IMIKTDVNYQ FTQIVVDRVD AEDGQYDVMF IGTDVGTVLK VVSVPKETWH DLEEILLEEM
       490        500        510        520        530        540
TVFREPTTIS AMELSTKQQQ LYIGSTAGVA QLPLHRCDIY GKACAECCLA RDPYCAWDGS
       550        560        570        580        590        600
SCSRYFPTAK RRTRRQDIRN GDPLTHCSDL QHHDNHHGPS LEERIIYGVE NSSTFLECSP
       610        620        630        640        650        660
KSQRALVYWQ FQRRNEDRKE EIRMGDHIIR TEQGLLLRSL QKKDSGNYLC HAVEHGFMQT
       670        680        690        700        710        720
LLKVTLEVID TEHLEELLHK DDDGDGSKIK EMSSSMTPSQ KVWYRDFMQL INHPNLNTMD
       730        740        750        760        770
EFCEQVWKRD RKQRRQRPGH SQGSSNKWKH MQESKKGRNR RTHEFERAPR SV

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O08665-21-unknown	NYANGK...	21	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O08665-278-unmodified	SLVNKW...	278		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
O08665-556-unknown	QDIRNG...	556	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32196

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HTFLLD	62	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122621
...RLYVGA	72	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121710
...RRTRRQ	555	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32196
...GDGSKI	688	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000128153
...APRSV	772	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
FURIN_MOUSE	555	TRRQ.\|.QDIR	inferred from experiment	unknown	MEROPS	Thomas G	Molloy SS et al.:Bi-cycling the furin pathway: f... (S08.071)	10087614,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)