O08808: Protein diaphanous homolog 1
Protein names | - Protein diaphanous homolog 1 - Diaphanous-related formin-1 - DRF1 - p140mDIA - mDIA1 {ECO:0000303|PubMed:23558171} |
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Gene names | Diaph1 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | O08808 |
4
N-termini
4
C-termini
4
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MEPSGGGLGP GRGTRDKKKG RSPDELPATG GDGGKHKKFL ERFTSMRIKK EKEKPNSAHR
70 80 90 100 110 120
NSSASYGDDP TAQSLQDISD EQVLVLFEQM LVDMNLNEEK QQPLREKDIV IKREMVSQYL
130 140 150 160 170 180
HTSKAGMNQK ESSRSAMMYI QELRSGLRDM HLLSCLESLR VSLNNNPVSW VQTFGAEGLA
190 200 210 220 230 240
SLLDILKRLH DEKEETSGNY DSRNQHEIIR CLKAFMNNKF GIKTMLETEE GILLLVRAMD
250 260 270 280 290 300
PAVPNMMIDA AKLLSALCIL PQPEDMNERV LEAMTERAEM DEVERFQPLL DGLKSGTSIA
310 320 330 340 350 360
LKVGCLQLIN ALITPAEELD FRVHIRSELM RLGLHQVLQE LREIENEDMK VQLCVFDEQG
370 380 390 400 410 420
DEDFFDLKGR LDDIRMEMDD FGEVFQIILN TVKDSKAEPH FLSILQHLLL VRNDYEARPQ
430 440 450 460 470 480
YYKLIEECVS QIVLHKNGTD PDFKCRHLQI DIERLVDQMI DKTKVEKSEA KATELEKKLD
490 500 510 520 530 540
SELTARHELQ VEMKKMENDF EQKLQDLQGE KDALDSEKQQ ITAQKQDLEA EVSKLTGEVA
550 560 570 580 590 600
KLSKELEDAK NEMASLSAVV VAPSVSSSAA VPPAPPLPGD SGTVIPPPPP PPPLPGGVVP
610 620 630 640 650 660
PSPPLPPGTC IPPPPPLPGG ACIPPPPQLP GSAAIPPPPP LPGVASIPPP PPLPGATAIP
670 680 690 700 710 720
PPPPLPGATA IPPPPPLPGG TGIPPPPPPL PGSVGVPPPP PLPGGPGLPP PPPPFPGAPG
730 740 750 760 770 780
IPPPPPGMGV PPPPPFGFGV PAAPVLPFGL TPKKVYKPEV QLRRPNWSKF VAEDLSQDCF
790 800 810 820 830 840
WTKVKEDRFE NNELFAKLTL AFSAQTKTSK AKKDQEGGEE KKSVQKKKVK ELKVLDSKTA
850 860 870 880 890 900
QNLSIFLGSF RMPYQEIKNV ILEVNEAVLT ESMIQNLIKQ MPEPEQLKML SELKEEYDDL
910 920 930 940 950 960
AESEQFGVVM GTVPRLRPRL NAILFKLQFS EQVENIKPEI VSVTAACEEL RKSENFSSLL
970 980 990 1000 1010 1020
ELTLLVGNYM NAGSRNAGAF GFNISFLCKL RDTKSADQKM TLLHFLAELC ENDHPEVLKF
1030 1040 1050 1060 1070 1080
PDELAHVEKA SRVSAENLQK SLDQMKKQIA DVERDVQNFP AATDEKDKFV EKMTSFVKDA
1090 1100 1110 1120 1130 1140
QEQYNKLRMM HSNMETLYKE LGDYFVFDPK KLSVEEFFMD LHNFRNMFLQ AVKENQKRRE
1150 1160 1170 1180 1190 1200
TEEKMRRAKL AKEKAEKERL EKQQKREQLI DMNAEGDETG VMDSLLEALQ SGAAFRRKRG
1210 1220 1230 1240 1250
PRQVNRKAGC AVTSLLASEL TKDDAMAPGP VKVPKKSEGV PTILEEAKEL VGRAS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
O08808-1-Acetylation | MEPSGG... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
O08808-1186-unknown | LEALQS... | 1186 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28644 | |||
O08808-1187-unknown | EALQSG... | 1187 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29493 | |||
O08808-1187-unknown | EALQSG... | 1187 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28645 | |||
O08808-1245-unknown | EEAKEL... | 1245 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29494 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...VMDSLL | 1185 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28644 | |||
...MDSLLE | 1186 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29493 | |||
...MDSLLE | 1186 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28645 | |||
...VPTILE | 1244 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC29494 | |||
...VGRAS | 1255 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATD_MOUSE | 1185 | DSLL.|.LEAL | inferred from experiment | unknown | MEROPS | Merops CATD_MOUSE -> DIAP1_MOUSE @1185 | ||
CATE_MOUSE | 1186 | SLLE.|.EALQ | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> DIAP1_MOUSE @1186 | ||
CATD_MOUSE | 1186 | SLLE.|.EALQ | inferred from experiment | unknown | MEROPS | Merops CATD_MOUSE -> DIAP1_MOUSE @1186 | ||
CATE_MOUSE | 1244 | TILE.|.EEAK | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> DIAP1_MOUSE @1244 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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