O14944: Proepiregulin
| Protein names | - Proepiregulin - Epiregulin - EPR |
|---|---|
| Gene names | EREG |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | O14944 |
4
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MTAGRRMEML CAGRVPALLL CLGFHLLQAV LSTTVIPSCI PGESSDNCTA LVQTEDNPRV
70 80 90 100 110 120
AQVSITKCSS DMNGYCLHGQ CIYLVDMSQN YCRCEVGYTG VRCEHFFLTV HQPLSKEYVA
130 140 150 160
LTVILIILFL ITVVGSTYYF CRWYRNRKSK EPKKEYERVT SGDPELPQV
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| O14944-30-unknown | VLSTTV... | 30 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| O14944-60-unknown | VAQVSI... | 60 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| O14944-63-unknown | VSITKC... | 63 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC108 | |||
| O14944-63-unknown | VSITKC... | 63 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| O14944-109-unknown | TVHQPL... | 109 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC109 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...PRVAQV | 62 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC108 | |||
| ...EHFFLT | 108 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...EHFFLT | 108 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC109 | |||
| ...ELPQV | 169 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ADA17_HUMAN | 62 | VAQV.|.VSIT | inferred from experiment | unknown | MEROPS | Lee DC | Sunnarborg SW et al.:Tumor necrosis factor-alpha con... (M12.217) | 11823465, |
| ADA17_HUMAN | 108 | FFLT.|.TVHQ | inferred from experiment | unknown | MEROPS | Lee DC | Sunnarborg SW et al.:Tumor necrosis factor-alpha con... (M12.217) | 11823465, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|