O15162: Phospholipid scramblase 1

General Information

Protein names	- Phospholipid scramblase 1 - PL scramblase 1 - Ca(2+)-dependent phospholipid scramblase 1 - Erythrocyte phospholipid scramblase - MmTRA1b
Gene names	PLSCR1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O15162

4 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDKQNSQMNA SHPETNLPVG YPPQYPPTAF QGPPGYSGYP GPQVSYPPPP AGHSGPGPAG
        70         80         90        100        110        120
FPVPNQPVYN QPVYNQPVGA AGVPWMPAPQ PPLNCPPGLE YLSQIDQILI HQQIELLEVL
       130        140        150        160        170        180
TGFETNNKYE IKNSFGQRVY FAAEDTDCCT RNCCGPSRPF TLRIIDNMGQ EVITLERPLR
       190        200        210        220        230        240
CSSCCCPCCL QEIEIQAPPG VPIGYVIQTW HPCLPKFTIQ NEKREDVLKI SGPCVVCSCC
       250        260        270        280        290        300
GDVDFEIKSL DEQCVVGKIS KHWTGILREA FTDADNFGIQ FPLDLDVKMK AVMIGACFLI
       310
DFMFFESTGS QEQKSGVW

Isoforms

- Isoform 2 of Phospholipid scramblase 1

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name
O15162-1-acetylation	MDKQNS...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O15162-1-unknown	MDKQNS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O15162-8-unknown	MNASHP...	8		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000417792
O15162-8-unknown	MNASHP...	8		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
O15162-289-unknown	MKAVMI...	289		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000414653

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FEIKSL	249	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000420523
...KSLDEQ	252	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418550
...REAFTD	272	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000418103
...IDFMFF	304	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000420006
...KSGVW	318	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)