O15392: Baculoviral IAP repeat-containing protein 5

General Information

Protein names	- Baculoviral IAP repeat-containing protein 5 - Apoptosis inhibitor 4 - Apoptosis inhibitor survivin
Gene names	BIRC5
Organism	Homo sapiens
Protease Family
Protease ID	I32.005
Chromosome location
UniProt ID	O15392

5 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Baculoviral IAP repeat-containing protein 5 - Isoform 3 of Baculoviral IAP repeat-containing protein 5 - Isoform 4 of Baculoviral IAP repeat-containing protein 5 - Isoform 5 of Baculoviral IAP repeat-containing protein 5 - Isoform 6 of Baculoviral IAP repeat-containing protein 5 - Isoform 7 of Baculoviral IAP repeat-containing protein 5

Sequence View

        10         20         30         40         50         60
MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC
        70         80         90        100        110        120
FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE FLKLDRERAK NKIAKETNNK
       130        140
KKEFEETAKK VRRAIEQLAA MD         10         20         30         40         50         60
MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC
        70         80         90        100        110        120
FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE FLKLDRERAK NKIAKETNNK
       130        140
KKEFEETAKK VRRAIEQLAA MD         10         20         30         40         50         60
MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC
        70         80         90        100        110        120
FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE FLKLDRERAK NKIAKETNNK
       130        140
KKEFEETAKK VRRAIEQLAA MD         10         20         30         40         50         60
MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC
        70         80         90        100        110        120
FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE FLKLDRERAK NKIAKETNNK
       130        140
KKEFEETAKK VRRAIEQLAA MD         10         20         30         40         50         60
MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC
        70         80         90        100        110        120
FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE FLKLDRERAK NKIAKETNNK
       130        140
KKEFEETAKK VRRAIEQLAA MD         10         20         30         40         50         60
MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC
        70         80         90        100        110        120
FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE FLKLDRERAK NKIAKETNNK
       130        140
KKEFEETAKK VRRAIEQLAA MD

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O15392-1-unknown	MGAPTL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O15392-1-unknown	MGAPTL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt68485
O15392-1-unknown	MGAPTL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt68486
O15392-1-unknown	MGAPTL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt68487
O15392-1-unknown	MGAPTL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt68488
O15392-1-unknown	MGAPTL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt68489
O15392-1-unknown	MGAPTL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt68490
O15392-2-	GAPTLP...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O15392-2-unknown	GAPTLP...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168201
O15392-2-unknown	GAPTLP...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168202
O15392-2-unknown	GAPTLP...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168203
O15392-2-unknown	GAPTLP...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168204
O15392-2-unknown	GAPTLP...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168205
O15392-2-unknown	GAPTLP...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168206
O15392-96-unknown	LTLGEF...	96	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177074
O15392-96-	LTLGEF...	96		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...LAAMD	142	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...LAAMD	142	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt64103
...LAAMD	142		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LAAMD	142		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...LAAMD	142		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...LAAMD	142		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)