O35188: Fractalkine
| Protein names | - Fractalkine - C-X3-C motif chemokine 1 - CX3C membrane-anchored chemokine - Neurotactin - Small-inducible cytokine D1 - Processed fractalkine |
|---|---|
| Gene names | Cx3cl1 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | O35188 |
3
N-termini
4
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAPSPLAWLL RLAAFFHLCT LLPGQHLGMT KCEIMCDKMT SRIPVALLIR YQLNQESCGK
70 80 90 100 110 120
RAIVLETTQH RRFCADPKEK WVQDAMKHLD HQAAALTKNG GKFEKRVDNV TPGITLATRG
130 140 150 160 170 180
LSPSALTKPE SATLEDLALE LTTISQEARG TMGTSQEPPA AVTGSSLSTS EAQDAGLTAK
190 200 210 220 230 240
PQSIGSFEAA DISTTVWPSP AVYQSGSSSW AEEKATESPS TTAPSPQVST TSPSTPEENV
250 260 270 280 290 300
GSEGQPPWVQ GQDLSPEKSL GSEEINPVHT DNFQERGPGN TVHPSVAPIS SEETPSPELV
310 320 330 340 350 360
ASGSQAPKIE EPIHATADPQ KLSVLITPVP DTQAATRRQA VGLLAFLGLL FCLGVAMFAY
370 380 390
QSLQGCPRKM AGEMVEGLRY VPRSCGSNSY VLVPV
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| O35188-25-unknown | QHLGMT... | 25 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| O35188-29-unknown | MTKCEI... | 29 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33138 | |||
| O35188-96-unknown | LTKNGG... | 96 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33139 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...GQHLGM | 28 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33138 | |||
| ...HQAAAL | 95 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33139 | |||
| ...QAATRR | 337 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...VLVPV | 395 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MMP2_MOUSE | 28 | HLGM.|.MTKC | inferred from experiment | unknown | MEROPS | Overall CM | Dean RA et al.:Proteomics discovery of metallo... (M10.003) | 17200105, |
| MMP2_MOUSE | 28 | HLGM.|.MTKC | inferred from experiment | unknown | MEROPS | Merops MMP2_MOUSE -> X3CL1_MOUSE @28 | ||
| MMP2_MOUSE | 95 | AAAL.|.LTKN | inferred from experiment | unknown | MEROPS | Overall CM | Dean RA et al.:Proteomics discovery of metallo... (M10.003) | 17200105, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|