O35417: Proenkephalin-B
| Protein names | - Proenkephalin-B - Beta-neoendorphin-dynorphin - Preprodynorphin - Alpha-neoendorphin - Beta-neoendorphin - Big dynorphin - Big Dyn - Dynorphin A(1-17) - Dyn-A17 - Dynorphin A - Dynorphin A(1-13) - Dynorphin A(1-8) - Leu-enkephalin - Rimorphin - Dynorphin B - Dyn-B - Dynorphin B(1-13) - Leumorphin - Dynorphin B-29 |
|---|---|
| Gene names | Pdyn |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | O35417 |
4
N-termini
3
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAWSRLMLAA CLLVMPSNVM ADCLSLCSLC AVRIQDGPRP INPLICSLEC QDLVPPSEEW
70 80 90 100 110 120
ETCRGFSSFL TLTVSGLRGK DDLEDEVALE EGISAHAKLL EPVLKELEKS RLLTSVPEEK
130 140 150 160 170 180
FRGLSSSFGN GKESELAGAD RMNDEAAQGR TVHFNEEDLR KQAKRYGGFL RKYPKRSSEM
190 200 210 220 230 240
ARDEDGGQDG DQVGHEDLYK RYGGFLRRIR PKLKWDNQKR YGGFLRRQFK VVTRSQENPN
TYSEDLDV
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| O35417-22-unknown | DCLSLC... | 22 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| O35417-166-unknown | YGGFLR... | 166 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34669 | |||
| O35417-177-unknown | SSEMAR... | 177 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34670 | |||
| O35417-228-unknown | QFKVVT... | 228 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31431 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...KQAKRY | 165 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34669 | |||
| ...KYPKRS | 176 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34670 | |||
| ...GFLRRQ | 227 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31431 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| NEC2_MOUSE | 165 | AKRY.|.YGGF | inferred from experiment | unknown | MEROPS | Fricker LD | Pan H et al.:The role of prohormone converta... (S08.073) | 16903874, |
| NEC2_MOUSE | 176 | PKRS.|.SSEM | inferred from experiment | unknown | MEROPS | Fricker LD | Pan H et al.:The role of prohormone converta... (S08.073) | 16903874, |
| CBPA4_MOUSE | 227 | LRRQ.|.QFKV | inferred from experiment | unknown | MEROPS | Fricker LD | Tanco S et al.:Characterization of the substra... (M14.017) | 20385563, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|