O43181: NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

General Information

Protein names	- NADH dehydrogenase ubiquinone] iron-sulfur protein 4, mitochondrial - Complex I-18 kDa - CI-18 kDa - Complex I-AQDQ - CI-AQDQ - NADH-ubiquinone oxidoreductase 18 kDa subunit
Gene names	NDUFS4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43181

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAVSMSVVL RQTLWRRRAV AVAALSVSRV PTRSLRTSTW RLAQDQTQDT QLITVDEKLD
        70         80         90        100        110        120
ITTLTGVPEE HIKTRKVRIF VPARNNMQSG VNNTKKWKME FDTRERWENP LMGWASTADP
       130        140        150        160        170
LSNMVLTFST KEDAVSFAEK NGWSYDIEER KVPKPKSKSY GANFSWNKRT RVSTK

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O43181-2-unknown	AAVSMS...	2	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
O43181-5-unknown	SMSVVL...	5	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000424570
O43181-43-unknown	AQDQTQ...	43	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O43181-43-unknown	AQDQTQ...	43		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O43181-43-unknown	AQDQTQ...	43	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
O43181-43-	AQDQTQ...	43		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
O43181-43-	AQDQTQ...	43		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
O43181-43-	AQDQTQ...	43		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O43181-43-	AQDQTQ...	43		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
O43181-43-	AQDQTQ...	43		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
O43181-43-	AQDQTQ...	43		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O43181-43-	AQDQTQ...	43		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O43181-43-	AQDQTQ...	43		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O43181-43-	AQDQTQ...	43		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
O43181-43-	AQDQTQ...	43		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...RVSTK	175	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)