O43242: 26S proteasome non-ATPase regulatory subunit 3

General Information

Protein names	- 26S proteasome non-ATPase regulatory subunit 3 - 26S proteasome regulatory subunit RPN3 - 26S proteasome regulatory subunit S3 - Proteasome subunit p58
Gene names	PSMD3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43242

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MKQEGSARRR GADKAKPPPG GGEQEPPPPP APQDVEMKEE AATGGGSTGE ADGKTAAAAA
        70         80         90        100        110        120
EHSQRELDTV TLEDIKEHVK QLEKAVSGKE PRFVLRALRM LPSTSRRLNH YVLYKAVQGF
       130        140        150        160        170        180
FTSNNATRDF LLPFLEEPMD TEADLQFRPR TGKAASTPLL PEVEAYLQLL VVIFMMNSKR
       190        200        210        220        230        240
YKEAQKISDD LMQKISTQNR RALDLVAAKC YYYHARVYEF LDKLDVVRSF LHARLRTATL
       250        260        270        280        290        300
RHDADGQATL LNLLLRNYLH YSLYDQAEKL VSKSVFPEQA NNNEWARYLY YTGRIKAIQL
       310        320        330        340        350        360
EYSEARRTMT NALRKAPQHT AVGFKQTVHK LLIVVELLLG EIPDRLQFRQ PSLKRSLMPY
       370        380        390        400        410        420
FLLTQAVRTG NLAKFNQVLD QFGEKFQADG TYTLIIRLRH NVIKTGVRMI SLSYSRISLA
       430        440        450        460        470        480
DIAQKLQLDS PEDAEFIVAK AIRDGVIEAS INHEKGYVQS KEMIDIYSTR EPQLAFHQRI
       490        500        510        520        530
SFCLDIHNMS VKAMRFPPKS YNKDLESAEE RREREQQDLE FAKEMAEDDD DSFP

Isoforms

- Isoform 2 of 26S proteasome non-ATPase regulatory subunit 3

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O43242-1-unknown	MKQEGS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O43242-1-unknown	MKQEGS...	1			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O43242-1-unknown	MKQEGS...	1			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O43242-1-unknown	MKQEGS...	1			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O43242-56-acetylation	AAAAAE...	56	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O43242-139-unknown	MDTEAD...	139		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000442508

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...DDSFP	534	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)