TopFIND 4.0

O43252: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

General Information

Protein names
- Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1
- PAPS synthase 1
- PAPSS 1
- Sulfurylase kinase 1
- SK 1
- SK1
- Sulfate adenylyltransferase
- 2.7.7.4 {ECO:0000269|PubMed:14747722, ECO:0000269|PubMed:9576487, ECO:0000269|PubMed:9648242, ECO:0000269|PubMed:9668121}
- ATP-sulfurylase
- Sulfate adenylate transferase
- SAT
- Adenylyl-sulfate kinase
- 2.7.1.25 {ECO:0000269|PubMed:14747722, ECO:0000269|PubMed:17276460, ECO:0000269|PubMed:17540769, ECO:0000269|PubMed:9576487, ECO:0000269|PubMed:9648242, ECO:0000269|PubMed:9668121}
- 3'-phosphoadenosine-5'-phosphosulfate synthase
- APS kinase
- Adenosine-5'-phosphosulfate 3'-phosphotransferase
- Adenylylsulfate 3'-phosphotransferase
Gene names PAPSS1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O43252

4

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEIPGSLCKK VKLSNNAQNW GMQRATNVTY QAHHVSRNKR GQVVGTRGGF RGCTVWLTGL 
        70         80         90        100        110        120 
SGAGKTTVSM ALEEYLVCHG IPCYTLDGDN IRQGLNKNLG FSPEDREENV RRIAEVAKLF 
       130        140        150        160        170        180 
ADAGLVCITS FISPYTQDRN NARQIHEGAS LPFFEVFVDA PLHVCEQRDV KGLYKKARAG 
       190        200        210        220        230        240 
EIKGFTGIDS EYEKPEAPEL VLKTDSCDVN DCVQQVVELL QERDIVPVDA SYEVKELYVP 
       250        260        270        280        290        300 
ENKLHLAKTD AETLPALKIN KVDMQWVQVL AEGWATPLNG FMREREYLQC LHFDCLLDGG 
       310        320        330        340        350        360 
VINLSVPIVL TATHEDKERL DGCTAFALMY EGRRVAILRN PEFFEHRKEE RCARQWGTTC 
       370        380        390        400        410        420 
KNHPYIKMVM EQGDWLIGGD LQVLDRVYWN DGLDQYRLTP TELKQKFKDM NADAVFAFQL 
       430        440        450        460        470        480 
RNPVHNGHAL LMQDTHKQLL ERGYRRPVLL LHPLGGWTKD DDVPLMWRMK QHAAVLEEGV 
       490        500        510        520        530        540 
LNPETTVVAI FPSPMMYAGP TEVQWHCRAR MVAGANFYIV GRDPAGMPHP ETGKDLYEPS 
       550        560        570        580        590        600 
HGAKVLTMAP GLITLEIVPF RVAAYNKKKK RMDYYDSEHH EDFEFISGTR MRKLAREGQK 
       610        620    
PPEGFMAPKA WTVLTEYYKS LEKA

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SLEKA 624 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)