O43447: Peptidyl-prolyl cis-trans isomerase H

General Information

Protein names	- Peptidyl-prolyl cis-trans isomerase H - PPIase H - 5.2.1.8 {ECO:0000269\|PubMed:20676357} - Rotamase H - Small nuclear ribonucleoprotein particle-specific cyclophilin H - CypH - U-snRNP-associated cyclophilin SnuCyp-20 - USA-CYP
Gene names	PPIH
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43447

4 N-termini

4 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAVANSSPVN PVVFFDVSIG GQEVGRMKIE LFADVVPKTA ENFRQFCTGE FRKDGVPIGY
        70         80         90        100        110        120
KGSTFHRVIK DFMIQGGDFV NGDGTGVASI YRGPFADENF KLRHSAPGLL SMANSGPSTN
       130        140        150        160        170
GCQFFITCSK CDWLDGKHVV FGKIIDGLLV MRKIENVPTG PNNKPKLPVV ISQCGEM

Isoforms

- Isoform 2 of Peptidyl-prolyl cis-trans isomerase H

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O43447-2-unknown	MAVANS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O43447-2-Acetylation	AVANSS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O43447-2-Acetylation	AVANSS...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O43447-2-Acetylation	AVANSS...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O43447-27-unknown	MKIELF...	27		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000402836
O43447-27-unknown	MKIELF...	27		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000361629
O43447-156-unknown	NVPTGP...	156		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5166

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...MRKIEN	155	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5166
...KLPVVI	170	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000402836
...QCGEM	177	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...QCGEM	177		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...QCGEM	177		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	155	KIEN.\|.NVPT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)