O43598: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255|HAMAP-Rule:MF_03036}

General Information

Protein names	- 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255\|HAMAP-Rule:MF_03036} - 3.2.2.- {ECO:0000255\|HAMAP-Rule:MF_03036, ECO:0000269\|PubMed:24260472, ECO:0000269\|PubMed:25108359} - c-Myc-responsive protein RCL {ECO:0000255\|HAMAP-Rule:MF_03036}
Gene names	DNPH1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43598

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAAMVPGRS ESWERGEPGR PALYFCGSIR GGREDRTLYE RIVSRLRRFG TVLTEHVAAA
        70         80         90        100        110        120
ELGARGEEAA GGDRLIHEQD LEWLQQADVV VAEVTQPSLG VGYELGRAVA FNKRILCLFR
       130        140        150        160        170
PQSGRVLSAM IRGAADGSRF QVWDYEEGEV EALLDRYFEA DPPGQVAASP DPTT

Isoforms

- Isoform 2 of 2'-deoxynucleoside 5'-phosphate N-hydrolase 1

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O43598-1-unknown	MAAAMV...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73093
O43598-2-unknown	MAAAMV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O43598-2-Acetylation	AAAMVP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O43598-2-Acetylation	AAAMVP...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O43598-2-Acetylation	AAAMVP...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
O43598-2-Acetylation	AAAMVP...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O43598-2-Acetylation	AAAMVP...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O43598-2-Acetylation	AAAMVP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111412

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...PDPTT	174		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...PDPTT	174		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...PDPTT	174	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...PDPTT	174		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...PDPTT	174		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)