O43889: Cyclic AMP-responsive element-binding protein 3

General Information

Protein names	- Cyclic AMP-responsive element-binding protein 3 - CREB-3 - cAMP-responsive element-binding protein 3 - Leucine zipper protein - Luman - Transcription factor LZIP-alpha - Processed cyclic AMP-responsive element-binding protein 3 - N-terminal Luman - Transcriptionally active form
Gene names	CREB3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43889

2 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Cyclic AMP-responsive element-binding protein 3 - Isoform 3 of Cyclic AMP-responsive element-binding protein 3 - Isoform 2 of Cyclic AMP-responsive element-binding protein 3

Sequence View

        10         20         30         40         50         60
MELELDAGDQ DLLAFLLEES GDLGTAPDEA VRAPLDWALP LSEVPSDWEV DDLLCSLLSP
        70         80         90        100        110        120
PASLNILSSS NPCLVHHDHT YSLPRETVSM DLESESCRKE GTQMTPQHME ELAEQEIARL
       130        140        150        160        170        180
VLTDEEKSLL EKEGLILPET LPLTKTEEQI LKRVRRKIRN KRSAQESRRK KKVYVGGLES
       190        200        210        220        230        240
RVLKYTAQNM ELQNKVQLLE EQNLSLLDQL RKLQAMVIEI SNKTSSSSTC ILVLLVSFCL
       250        260        270        280        290        300
LLVPAMYSSD TRGSLPAEHG VLSRQLRALP SEDPYQLELP ALQSEVPKDS THQWLDGSDC
       310        320        330        340        350        360
VLQAPGNTSC LLHYMPQAPS AEPPLEWPFP DLFSEPLCRG PILPLQANLT RKGGWLPTGS
       370
PSVILQDRYS G         10         20         30         40         50         60
MELELDAGDQ DLLAFLLEES GDLGTAPDEA VRAPLDWALP LSEVPSDWEV DDLLCSLLSP
        70         80         90        100        110        120
PASLNILSSS NPCLVHHDHT YSLPRETVSM DLESESCRKE GTQMTPQHME ELAEQEIARL
       130        140        150        160        170        180
VLTDEEKSLL EKEGLILPET LPLTKTEEQI LKRVRRKIRN KRSAQESRRK KKVYVGGLES
       190        200        210        220        230        240
RVLKYTAQNM ELQNKVQLLE EQNLSLLDQL RKLQAMVIEI SNKTSSSSTC ILVLLVSFCL
       250        260        270        280        290        300
LLVPAMYSSD TRGSLPAEHG VLSRQLRALP SEDPYQLELP ALQSEVPKDS THQWLDGSDC
       310        320        330        340        350        360
VLQAPGNTSC LLHYMPQAPS AEPPLEWPFP DLFSEPLCRG PILPLQANLT RKGGWLPTGS
       370
PSVILQDRYS G         10         20         30         40         50         60
MELELDAGDQ DLLAFLLEES GDLGTAPDEA VRAPLDWALP LSEVPSDWEV DDLLCSLLSP
        70         80         90        100        110        120
PASLNILSSS NPCLVHHDHT YSLPRETVSM DLESESCRKE GTQMTPQHME ELAEQEIARL
       130        140        150        160        170        180
VLTDEEKSLL EKEGLILPET LPLTKTEEQI LKRVRRKIRN KRSAQESRRK KKVYVGGLES
       190        200        210        220        230        240
RVLKYTAQNM ELQNKVQLLE EQNLSLLDQL RKLQAMVIEI SNKTSSSSTC ILVLLVSFCL
       250        260        270        280        290        300
LLVPAMYSSD TRGSLPAEHG VLSRQLRALP SEDPYQLELP ALQSEVPKDS THQWLDGSDC
       310        320        330        340        350        360
VLQAPGNTSC LLHYMPQAPS AEPPLEWPFP DLFSEPLCRG PILPLQANLT RKGGWLPTGS
       370
PSVILQDRYS G

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O43889-1-unknown	MELELD...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O43889-1-unknown	MELELD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71665
O43889-1-unknown	MELELD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71666
O43889-292-unknown	HQWLDG...	292	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16818
O43889-292-unknown	HQWLDG...	292	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt148445
O43889-292-unknown	HQWLDG...	292	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149080
O43889-292-unknown	HQWLDG...	292	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...	0	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PKDSTH	291	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16818
...	395	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...	395	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67284
...	395	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67283

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MBTP1_HUMAN	291	DSTH.\|.HQWL	inferred from experiment	unknown	MEROPS	Seidah NG	Pasquato A et al.:The proprotein convertase SKI-1... (S08.063)	16790437,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)