O54824: Pro-interleukin-16
Protein names | - Pro-interleukin-16 - Interleukin-16 - IL-16 - Lymphocyte chemoattractant factor - LCF |
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Gene names | Il16 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | O54824 |
4
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MEPHGHSGKS RKSTKFRSIS RSLILCNAKT SDDGSSPDEK YPDPFETSLC QGKEGFFHSS
70 80 90 100 110 120
MQLADTFEAG LSNIPDLALA SDSAQLAAAG SDRGKHCRKM FFMKESSSTS SKEKSGKPEA
130 140 150 160 170 180
QSSSFLFPKA CHQRTRSNST SVNPYSAGEI DFPMTKKSAA PTDRQPYSLC SNRKSLSQQL
190 200 210 220 230 240
DYPILGTARP TRSLSTAQLG QLSGGLQASV ISNIVLMKGQ AKGLGFSIVG GKDSIYGPIG
250 260 270 280 290 300
IYVKSIFAGG AAAADGRLQE GDEILELNGE SMAGLTHQDA LQKFKQAKKG LLTLTVRTRL
310 320 330 340 350 360
TTPPSLCSHL SPPLCRSLSS STCGAQDSSP FSLESPASPA STAKPNYRIM VEVSLKKEAG
370 380 390 400 410 420
VGLGIGLCSI PYFQCISGIF VHTLSPGSVA HLDGRLRCGD EIVEINDSPV HCLTLNEVYT
430 440 450 460 470 480
ILSHCDPGPV PIIVSRHPDP QVSEQQLKEA VAQAVEGVKF GKDRHQWSLE GVKRLESSWH
490 500 510 520 530 540
GRPTLEKERE KHSAPPHRRA QKIMVRSSSD SSYMSGSPGG SPCSAGAEPQ PSEREGSTHS
550 560 570 580 590 600
PSLSPGEEQE PCPGVPSRPQ QESPPLPESL ERESHPPLRL KKSFEILVRK PTSSKPKPPP
610 620 630 640 650 660
RKYFKNDSEP QKKLEEKEKV TDPSGHTLPT CSQETRELLP LLLQEDTAGR APCTAACCPG
670 680 690 700 710 720
PAASTQTSSS TEGESRRSAS PETPASPGKH PLLKRQARMD YSFDITAEDP WVRISDCIKN
730 740 750 760 770 780
LFSPIMSENH SHTPLQPNTS LGEEDGTQGC PEGGLSKMDA ANGAPRVYKS ADGSTVKKGP
790 800 810 820 830 840
PVAPKPAWFR QSLKGLRNRA PDPRRPPEVA SAIQPTPVSR DPPGPQPQAS SSIRQRISSF
850 860 870 880 890 900
ENFGSSQLPD RGVQRLSLQP SSGETTKFPG KQDGGRFSGL LGQGATVTAK HRQTEVESMS
910 920 930 940 950 960
TTFPNSSEVR DPGLPESPPP GQRPSTKALS PDPLLRLLTT QSEDTQGPGL KMPSQRARSF
970 980 990 1000 1010 1020
PLTRTQSCET KLLDEKASKL YSISSQLSSA VMKSLLCLPS SVSCGQITCI PKERVSPKSP
1030 1040 1050 1060 1070 1080
CNNSSAAEGF GEAMASDTGF SLNLSELREY SEGLTEPGET EDRNHCSSQA GQSVISLLSA
1090 1100 1110 1120 1130 1140
EELEKLIEEV RVLDEATLKQ LDSIHVTILH KEEGAGLGFS LAGGADLENK VITVHRVFPN
1150 1160 1170 1180 1190 1200
GLASQEGTIQ KGNEVLSING KSLKGATHND ALAILRQARD PRQAVIVTRR TTVEATHDLN
1210 1220 1230 1240 1250 1260
SSTDSAASAS AASDISVESK EATVCTVTLE KTSAGLGFSL EGGKGSLHGD KPLTINRIFK
1270 1280 1290 1300 1310 1320
GTEQGEMVQP GDEILQLAGT AVQGLTRFEA WNVIKALPDG PVTIVIRRTS LQCKQTTASA
DS
Isoforms
- Isoform 2 of Pro-interleukin-16Sequence View
10 20 30 40 50 60
MEPHGHSGKS RKSTKFRSIS RSLILCNAKT SDDGSSPDEK YPDPFETSLC QGKEGFFHSS
70 80 90 100 110 120
MQLADTFEAG LSNIPDLALA SDSAQLAAAG SDRGKHCRKM FFMKESSSTS SKEKSGKPEA
130 140 150 160 170 180
QSSSFLFPKA CHQRTRSNST SVNPYSAGEI DFPMTKKSAA PTDRQPYSLC SNRKSLSQQL
190 200 210 220 230 240
DYPILGTARP TRSLSTAQLG QLSGGLQASV ISNIVLMKGQ AKGLGFSIVG GKDSIYGPIG
250 260 270 280 290 300
IYVKSIFAGG AAAADGRLQE GDEILELNGE SMAGLTHQDA LQKFKQAKKG LLTLTVRTRL
310 320 330 340 350 360
TTPPSLCSHL SPPLCRSLSS STCGAQDSSP FSLESPASPA STAKPNYRIM VEVSLKKEAG
370 380 390 400 410 420
VGLGIGLCSI PYFQCISGIF VHTLSPGSVA HLDGRLRCGD EIVEINDSPV HCLTLNEVYT
430 440 450 460 470 480
ILSHCDPGPV PIIVSRHPDP QVSEQQLKEA VAQAVEGVKF GKDRHQWSLE GVKRLESSWH
490 500 510 520 530 540
GRPTLEKERE KHSAPPHRRA QKIMVRSSSD SSYMSGSPGG SPCSAGAEPQ PSEREGSTHS
550 560 570 580 590 600
PSLSPGEEQE PCPGVPSRPQ QESPPLPESL ERESHPPLRL KKSFEILVRK PTSSKPKPPP
610 620 630 640 650 660
RKYFKNDSEP QKKLEEKEKV TDPSGHTLPT CSQETRELLP LLLQEDTAGR APCTAACCPG
670 680 690 700 710 720
PAASTQTSSS TEGESRRSAS PETPASPGKH PLLKRQARMD YSFDITAEDP WVRISDCIKN
730 740 750 760 770 780
LFSPIMSENH SHTPLQPNTS LGEEDGTQGC PEGGLSKMDA ANGAPRVYKS ADGSTVKKGP
790 800 810 820 830 840
PVAPKPAWFR QSLKGLRNRA PDPRRPPEVA SAIQPTPVSR DPPGPQPQAS SSIRQRISSF
850 860 870 880 890 900
ENFGSSQLPD RGVQRLSLQP SSGETTKFPG KQDGGRFSGL LGQGATVTAK HRQTEVESMS
910 920 930 940 950 960
TTFPNSSEVR DPGLPESPPP GQRPSTKALS PDPLLRLLTT QSEDTQGPGL KMPSQRARSF
970 980 990 1000 1010 1020
PLTRTQSCET KLLDEKASKL YSISSQLSSA VMKSLLCLPS SVSCGQITCI PKERVSPKSP
1030 1040 1050 1060 1070 1080
CNNSSAAEGF GEAMASDTGF SLNLSELREY SEGLTEPGET EDRNHCSSQA GQSVISLLSA
1090 1100 1110 1120 1130 1140
EELEKLIEEV RVLDEATLKQ LDSIHVTILH KEEGAGLGFS LAGGADLENK VITVHRVFPN
1150 1160 1170 1180 1190 1200
GLASQEGTIQ KGNEVLSING KSLKGATHND ALAILRQARD PRQAVIVTRR TTVEATHDLN
1210 1220 1230 1240 1250 1260
SSTDSAASAS AASDISVESK EATVCTVTLE KTSAGLGFSL EGGKGSLHGD KPLTINRIFK
1270 1280 1290 1300 1310 1320
GTEQGEMVQP GDEILQLAGT AVQGLTRFEA WNVIKALPDG PVTIVIRRTS LQCKQTTASA
DS
Protein Neighborhood
Domains & Features
4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
O54824-1-unknown | MEPHGH... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
O54824-699-unknown | MDYSFD... | 699 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt77727 | |||
O54824-938-unknown | LTTQSE... | 938 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28659 | |||
O54824-938-unknown | LTTQSE... | 938 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt148095 | |||
O54824-1205-unknown | SAASAS... | 1205 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
O54824-1205-unknown | SAASAS... | 1205 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116468 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...PLLRLL | 937 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC28659 | |||
...PLLRLL | 937 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt131459 | |||
...ASADS | 1322 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...ASADS | 1322 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt73345 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATD_MOUSE | 937 | LRLL.|.LTTQ | inferred from experiment | unknown | MEROPS | Merops CATD_MOUSE -> IL16_MOUSE @937 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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