O55135: Eukaryotic translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_03132}

General Information

Protein names	- Eukaryotic translation initiation factor 6 {ECO:0000255\|HAMAP-Rule:MF_03132} - eIF-6 {ECO:0000255\|HAMAP-Rule:MF_03132} - B4 integrin interactor - CAB - p27(BBP)
Gene names	Eif6
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O55135

5 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAVRASFENN CEVGCFAKLT NAYCLVAIGG SENFYSVFEG ELSDAIPVVH ASIAGCRIIG
        70         80         90        100        110        120
RMCVGNRHGL LVPNNTTDQE LQHIRNSLPD SVQIRRVEER LSALGNVTTC NDYVALVHPD
       130        140        150        160        170        180
LDRETEEILA DVLKVEVFRQ TVADQVLVGS YCVFSNQGGL VHPKTSIEDQ DELSSLLQVP
       190        200        210        220        230        240
LVAGTVNRGS EVIAAGMVVN DWCAFCGLDT TSTELSVVES VFKLNEAKPS TIATSMRDSL

IDSLT

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O55135-1-unknown	MAVRAS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O55135-62-unknown	MCVGNR...	62	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000123190
O55135-104-unknown	LGNVTT...	104	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33158
O55135-107-unknown	VTTCND...	107	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33159
O55135-111-unmodified	NDYVAL...	111		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ERLSAL	103	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33158
...SALGNV	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33159
...ALVHPD	119	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123190
...IDSLT	245	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	103	LSAL.\|.LGNV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	106	LGNV.\|.VTTC	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)