O60486: Plexin-C1

General Information

Protein names	- Plexin-C1 - Virus-encoded semaphorin protein receptor - CD232
Gene names	PLXNC1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O60486

4 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEVSRRKAPP RPPRPAAPLP LLAYLLALAA PGRGADEPVW RSEQAIGAIA ASQEDGVFVA
        70         80         90        100        110        120
SGSCLDQLDY SLEHSLSRLY RDQAGNCTEP VSLAPPARPR PGSSFSKLLL PYREGAAGLG
       130        140        150        160        170        180
GLLLTGWTFD RGACEVRPLG NLSRNSLRNG TEVVSCHPQG STAGVVYRAG RNNRWYLAVA
       190        200        210        220        230        240
ATYVLPEPET ASRCNPAASD HDTAIALKDT EGRSLATQEL GRLKLCEGAG SLHFVDAFLW
       250        260        270        280        290        300
NGSIYFPYYP YNYTSGAATG WPSMARIAQS TEVLFQGQAS LDCGHGHPDG RRLLLSSSLV
       310        320        330        340        350        360
EALDVWAGVF SAAAGEGQER RSPTTTALCL FRMSEIQARA KRVSWDFKTA ESHCKEGDQP
       370        380        390        400        410        420
ERVQPIASST LIHSDLTSVY GTVVMNRTVL FLGTGDGQLL KVILGENLTS NCPEVIYEIK
       430        440        450        460        470        480
EETPVFYKLV PDPVKNIYIY LTAGKEVRRI RVANCNKHKS CSECLTATDP HCGWCHSLQR
       490        500        510        520        530        540
CTFQGDCVHS ENLENWLDIS SGAKKCPKIQ IIRSSKEKTT VTMVGSFSPR HSKCMVKNVD
       550        560        570        580        590        600
SSRELCQNKS QPNRTCTCSI PTRATYKDVS VVNVMFSFGS WNLSDRFNFT NCSSLKECPA
       610        620        630        640        650        660
CVETGCAWCK SARRCIHPFT ACDPSDYERN QEQCPVAVEK TSGGGRPKEN KGNRTNQALQ
       670        680        690        700        710        720
VFYIKSIEPQ KVSTLGKSNV IVTGANFTRA SNITMILKGT STCDKDVIQV SHVLNDTHMK
       730        740        750        760        770        780
FSLPSSRKEM KDVCIQFDGG NCSSVGSLSY IALPHCSLIF PATTWISGGQ NITMMGRNFD
       790        800        810        820        830        840
VIDNLIISHE LKGNINVSEY CVATYCGFLA PSLKSSKVRT NVTVKLRVQD TYLDCGTLQY
       850        860        870        880        890        900
REDPRFTGYR VESEVDTELE VKIQKENDNF NISKKDIEIT LFHGENGQLN CSFENITRNQ
       910        920        930        940        950        960
DLTTILCKIK GIKTASTIAN SSKKVRVKLG NLELYVEQES VPSTWYFLIV LPVLLVIVIF
       970        980        990       1000       1010       1020
AAVGVTRHKS KELSRKQSQQ LELLESELRK EIRDGFAELQ MDKLDVVDSF GTVPFLDYKH
      1030       1040       1050       1060       1070       1080
FALRTFFPES GGFTHIFTED MHNRDANDKN ESLTALDALI CNKSFLVTVI HTLEKQKNFS
      1090       1100       1110       1120       1130       1140
VKDRCLFASF LTIALQTKLV YLTSILEVLT RDLMEQCSNM QPKLMLRRTE SVVEKLLTNW
      1150       1160       1170       1180       1190       1200
MSVCLSGFLR ETVGEPFYLL VTTLNQKINK GPVDVITCKA LYTLNEDWLL WQVPEFSTVA
      1210       1220       1230       1240       1250       1260
LNVVFEKIPE NESADVCRNI SVNVLDCDTI GQAKEKIFQA FLSKNGSPYG LQLNEIGLEL
      1270       1280       1290       1300       1310       1320
QMGTRQKELL DIDSSSVILE DGITKLNTIG HYEISNGSTI KVFKKIANFT SDVEYSDDHC
      1330       1340       1350       1360       1370       1380
HLILPDSEAF QDVQGKRHRG KHKFKVKEMY LTKLLSTKVA IHSVLEKLFR SIWSLPNSRA
      1390       1400       1410       1420       1430       1440
PFAIKYFFDF LDAQAENKKI TDPDVVHIWK TNSLPLRFWV NILKNPQFVF DIKKTPHIDG
      1450       1460       1470       1480       1490       1500
CLSVIAQAFM DAFSLTEQQL GKEAPTNKLL YAKDIPTYKE EVKSYYKAIR DLPPLSSSEM
      1510       1520       1530       1540       1550       1560
EEFLTQESKK HENEFNEEVA LTEIYKYIVK YFDEILNKLE RERGLEEAQK QLLHVKVLFD

EKKKCKWM

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O60486-35-unknown	ADEPVW...	35	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O60486-385-unknown	MNRTVL...	385	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000447843
O60486-1009-	SFGTVP...	1009		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O60486-1009-	SFGTVP...	1009		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O60486-1262-unknown	MGTRQK...	1262	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000439225

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HSENLE	493	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000447843
...FLVTVI	1069	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000447625
...KCKWM	1568	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)