O60493: Sorting nexin-3

General Information

Protein names	- Sorting nexin-3 - Protein SDP3
Gene names	SNX3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O60493

7 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Sorting nexin-3 - Isoform 3 of Sorting nexin-3 - Isoform 4 of Sorting nexin-3

Sequence View

        10         20         30         40         50         60
MAETVADTRR LITKPQNLND AYGPPSNFLE IDVSNPQTVG VGRGRFTTYE IRVKTNLPIF
        70         80         90        100        110        120
KLKESTVRRR YSDFEWLRSE LERESKVVVP PLPGKAFLRQ LPFRGDDGIF DDNFIEERKQ
       130        140        150        160
GLEQFINKVA GHPLAQNERC LHMFLQDEII DKSYTPSKIR HA         10         20         30         40         50         60
MAETVADTRR LITKPQNLND AYGPPSNFLE IDVSNPQTVG VGRGRFTTYE IRVKTNLPIF
        70         80         90        100        110        120
KLKESTVRRR YSDFEWLRSE LERESKVVVP PLPGKAFLRQ LPFRGDDGIF DDNFIEERKQ
       130        140        150        160
GLEQFINKVA GHPLAQNERC LHMFLQDEII DKSYTPSKIR HA         10         20         30         40         50         60
MAETVADTRR LITKPQNLND AYGPPSNFLE IDVSNPQTVG VGRGRFTTYE IRVKTNLPIF
        70         80         90        100        110        120
KLKESTVRRR YSDFEWLRSE LERESKVVVP PLPGKAFLRQ LPFRGDDGIF DDNFIEERKQ
       130        140        150        160
GLEQFINKVA GHPLAQNERC LHMFLQDEII DKSYTPSKIR HA

Filter Information:

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O60493-1-unknown	MAETVA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90193
O60493-1-unknown	MAETVA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90194
O60493-1-unknown	MAETVA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90195
O60493-2-unknown	MAETVA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O60493-2-Acetylation	AETVAD...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O60493-2-Acetylation	AETVAD...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O60493-2-Acetylation	AETVAD...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O60493-2-Acetylation	AETVAD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111710
O60493-2-Acetylation	AETVAD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111711
O60493-2-Acetylation	AETVAD...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111712
O60493-21-	AYGPPS...	21			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O60493-21-unknown	AYGPPS...	21		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175971
O60493-21-unknown	AYGPPS...	21		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175972
O60493-33-unknown	VSNPQT...	33		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171475
O60493-33-unknown	VSNPQT...	33		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171476
O60493-33-	VSNPQT...	33			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O60493-33-	VSNPQT...	33			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KIRHA	162	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KIRHA	162	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85811
...KIRHA	162	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85813

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)