TopFIND 4.0

O70138: Neutrophil collagenase

General Information

Protein names
- Neutrophil collagenase
- 3.4.24.34
- Collagenase 2
- Matrix metalloproteinase-8
- MMP-8
Gene names Mmp8
Organism Mus musculus
Protease Family M10.002
Protease ID M10.002
Chromosome location
UniProt ID O70138

3

N-termini

1

C-termini

0

Cleavages

55

Substrates

Sequence

        10         20         30         40         50         60 
MFRLKTLPLL IFLHTQLANA FPVPEHLEEK NIKTAENYLR KFYNLPSNQF RSSRNATMVA 
        70         80         90        100        110        120 
EKLKEMQRFF SLAETGKLDA ATMGIMEMPR CGVPDSGDFL LTPGSPKWTH TNLTYRIINH 
       130        140        150        160        170        180 
TPQLSRAEVK TAIEKAFHVW SVASPLTFTE ILQGEADINI AFVSRDHGDN SPFDGPNGIL 
       190        200        210        220        230        240 
AHAFQPGQGI GGDAHFDSEE TWTQDSKNYN LFLVAAHEFG HSLGLSHSTD PGALMYPNYA 
       250        260        270        280        290        300 
YREPSTYSLP QDDINGIQTI YGPSDNPIQP TGPSTPKACD PHLRFDATTT LRGEIYFFKD 
       310        320        330        340        350        360 
KYFWRRHPQL RTVDLNFISL FWPFLPNGLQ AAYEDFDRDL VFLFKGRQYW ALSGYDLQQG 
       370        380        390        400        410        420 
YPRDISNYGF PRSVQAIDAA VSYNGKTYFF INNQCWRYDN QRRSMDPGYP KSIPSMFPGV 
       430        440        450        460    
NCRVDAVFLQ DSFFLFFSGP QYFAFNFVSH RVTRVARSNL WLNCS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 55 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...WLNCS 465 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates