Q61092: Laminin subunit gamma-2

General Information

Protein names	- Laminin subunit gamma-2 - Epiligrin subunit gamma - Kalinin subunit gamma - Kalinin/nicein/epiligrin 100 kDa subunit - Laminin B2t chain - Laminin-5 subunit gamma - Nicein subunit gamma
Gene names	Lamc2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q61092

4 N-termini

4 C-termini

9 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPALWLSCCL GVALLLPAAQ ATSRREVCDC NGKSRQCVFD QELHRQTGSG FRCLNCNDNT
        70         80         90        100        110        120
AGVHCERCRE GFYRHRDRDR CLPCNCHSKG SLSAGCDNSG QCRCKPGVTG QRCDRCQPGF
       130        140        150        160        170        180
HMLTDAGCTR DQGQLDSKCD CDPAGISGPC DSGRCVCKPA VTGERCDRCR PGYYHLDRAN
       190        200        210        220        230        240
PEGCTQCFCY GHSASCHASA DFSVHKITST FSQDVDGWKA VQRNGAPAKL HWSQRHRDVF
       250        260        270        280        290        300
SSARRSDPVY FVAPAKFLGN QQVSYGQSLS FDYRVDRGGR QPSAYDVILE GAGLQIRAPL
       310        320        330        340        350        360
MAPGKTLPCG ITKTYTFRLN EHPSSHWSPQ LSYFEYRRLL RNLTALLIRA TYGEYSTGYI
       370        380        390        400        410        420
DNVTLVSARP VSGAPAPWVE RCVCPAGYKG QFCQECASGY KRDSARLGPF GACVPCNCQG
       430        440        450        460        470        480
GGACDPDTGD CYSGDENPDI ECADCPIGFY NDPHDPRSCK PCPCHNGFSC SVMPETEEVV
       490        500        510        520        530        540
CNNCPPGVTG ARCELCADGF FGDPFGERGP VRPCQRCQCN NNVDPNASGN CDQLTGRCLK
       550        560        570        580        590        600
CIYNTAGVYC DQCKAGYFGD PLAPNPADKC RACNCSPMGS EPGECRGDGS CVCKPGFGGL
       610        620        630        640        650        660
NCDHAALTSC PACYNQVKIQ MDQFTQQLQS LEALVSKAQG GGGGGTVPVQ LEGRIEQAEQ
       670        680        690        700        710        720
ALQDILGEAQ ISEGAMRAVA VRLAKARSQE NDYKTRLDDL KMTAERIRAL GSQHQNRVQD
       730        740        750        760        770        780
TSRLISQMRL SLAGSEALLE NTNIHSSEHY VGPNDFKSLA QEATRKADSH AESANAMKQL
       790        800        810        820        830        840
ARETEDYSKQ ALSLARKLLS GGGGSGSWDS SVVQGLMGKL EKTKSLSQQL SLEGTQADIE
       850        860        870        880        890        900
ADRSYQHSLR LLDSASQLQG VSDLSFQVEA KRIRQKADSL SNLVTRQTDA FTRVRNNLGN
       910        920        930        940        950        960
WEKETRQLLQ TGKDRRQTSD QLLSRANLAK NRAQEALSMG NATFYEVENI LKNLREFDLQ
       970        980        990       1000       1010       1020
VEDRKAEAEE AMKRLSSISQ KVADASDKTQ QAETALGSAT ADTQRAKNAA REALEISSEI
      1030       1040       1050       1060       1070       1080
ELEIGSLNLE ANVTADGALA MEKGTATLKS EMREMIELAR KELEFDTDKD TVQLVITEAQ
      1090       1100       1110       1120       1130       1140
QADARATSAG VTIQDTLNTL DGILHLIDQP GSVDEEGMML LEQGLFQAKT QINSRLRPLM
      1150       1160       1170       1180       1190
SDLEERVRRQ RNHLHLLETS IDGILADVKN LENIRDNLPP GCYNTQALEQ Q

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 9 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q61092-22-unknown	TSRREV...	22	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q61092-435-unknown	DENPDI...	435	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32863
Q61092-435-unknown	DENPDI...	435	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28312
Q61092-435-unknown	DENPDI...	435	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32747
Q61092-607-unknown	LTSCPA...	607	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33054
Q61092-607-unknown	LTSCPA...	607	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34432
Q61092-607-unknown	LTSCPA...	607	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33933
Q61092-607-unknown	LTSCPA...	607	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32748
Q61092-607-unknown	LTSCPA...	607	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32752
Q61092-608-unknown	TSCPAC...	608	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34505

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DCYSGD	434	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32863
...DCYSGD	434	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28312
...DCYSGD	434	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32747
...CDHAAL	606	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33054
...CDHAAL	606	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34432
...CDHAAL	606	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33933
...CDHAAL	606	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32748
...CDHAAL	606	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32752
...DHAALT	607	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34505
...ALEQQ	1191	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP14_MOUSE	434	YSGD.\|.DENP	inferred from experiment	unknown	MEROPS	Maisi P	Pirila E et al.:Matrix metalloproteinases proce... (M10.009)	12684035,
BMP1_MOUSE	434	YSGD.\|.DENP	inferred from experiment	unknown	MEROPS	Marinkovich MP	Veitch DP et al.:Mammalian tolloid metalloprotei... (M12.005)	12473650,
MMP12_MOUSE	434	YSGD.\|.DENP	inferred from experiment	unknown	MEROPS	Maisi P	Pirila E et al.:Matrix metalloproteinases proce... (M10.009)	12684035,
MMP20_MOUSE	606	HAAL.\|.LTSC	inferred from experiment	unknown	MEROPS	Maisi P	Pirila E et al.:Matrix metalloproteinases proce... (M10.009)	12684035,
MMP3_MOUSE	606	HAAL.\|.LTSC	inferred from experiment	unknown	MEROPS	Maisi P	Pirila E et al.:Matrix metalloproteinases proce... (M10.009)	12684035,
MMP2_MOUSE	606	HAAL.\|.LTSC	inferred from experiment	unknown	MEROPS	Quaranta V	Giannelli G et al.:Induction of cell migration by ... (M10.003)	9211848,
MMP12_MOUSE	606	HAAL.\|.LTSC	inferred from experiment	unknown	MEROPS	Maisi P	Pirila E et al.:Matrix metalloproteinases proce... (M10.009)	12684035,
MMP13_MOUSE	606	HAAL.\|.LTSC	inferred from experiment	unknown	MEROPS	Maisi P	Pirila E et al.:Matrix metalloproteinases proce... (M10.009)	12684035,
MMP8_MOUSE	607	AALT.\|.TSCP	inferred from experiment	unknown	MEROPS	Maisi P	Pirila E et al.:Matrix metalloproteinases proce... (M10.009)	12684035,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)