TopFIND 4.0

P53690: Matrix metalloproteinase-14

General Information

Protein names
- Matrix metalloproteinase-14
- MMP-14
- 3.4.24.80
- MMP-X1
- MT-MMP
- Membrane-type matrix metalloproteinase 1
- MT-MMP 1
- MTMMP1
- Membrane-type-1 matrix metalloproteinase
- MT1-MMP
- MT1MMP
Gene names Mmp14
Organism Mus musculus
Protease Family M10.014
Protease ID M10.014
Chromosome location
UniProt ID P53690

2

N-termini

1

C-termini

0

Cleavages

111

Substrates

Sequence

        10         20         30         40         50         60 
MSPAPRPSRS LLLPLLTLGT ALASLGWAQG SNFSPEAWLQ QYGYLPPGDL RTHTQRSPQS 
        70         80         90        100        110        120 
LSAAIAAMQK FYGLQVTGKA DLATMMAMRR PRCGVPDKFG TEIKANVRRK RYAIQGLKWQ 
       130        140        150        160        170        180 
HNEITFCIQN YTPKVGEYAT FEAIRKAFRV WESATPLRFR EVPYAYIREG HEKQADIMIL 
       190        200        210        220        230        240 
FAEGFHGDST PFDGEGGFLA HAYFPGPNIG GDTHFDSAEP WTVQNEDLNG NDIFLVAVHE 
       250        260        270        280        290        300 
LGHALGLEHS NDPSAIMAPF YQWMDTENFV LPDDDRRGIQ QLYGSKSGSP TKMPPQPRTT 
       310        320        330        340        350        360 
SRPSVPDKPK NPAYGPNICD GNFDTVAMLR GEMFVFKERW FWRVRNNQVM DGYPMPIGQF 
       370        380        390        400        410        420 
WRGLPASINT AYERKDGKFV FFKGDKHWVF DEASLEPGYP KHIKELGRGL PTDKIDAALF 
       430        440        450        460        470        480 
WMPNGKTYFF RGNKYYRFNE EFRAVDSEYP KNIKVWEGIP ESPRGSFMGS DEVFTYFYKG 
       490        500        510        520        530        540 
NKYWKFNNQK LKVEPGYPKS ALRDWMGCPS GGRPDEGTEE ETEVIIIEVD EEGSGAVSAA 
       550        560        570        580    
AVVLPVLLLL LVLAVGLAVF FFRRHGTPKR LLYCQRSLLD KV

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 111 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LLDKV 582 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates