P33435: Collagenase 3
Protein names | - Collagenase 3 - 3.4.24.- - Matrix metalloproteinase-13 - MMP-13 |
---|---|
Gene names | Mmp13 |
Organism | Mus musculus |
Protease Family | M10.013 |
Protease ID | M10.013 |
Chromosome location | |
UniProt ID | P33435 |
2
N-termini
1
C-termini
0
Cleavages
4
Substrates
Sequence
10 20 30 40 50 60
MHSAILATFF LLSWTPCWSL PLPYGDDDDD DLSEEDLVFA EHYLKSYYHP ATLAGILKKS
70 80 90 100 110 120
TVTSTVDRLR EMQSFFGLEV TGKLDDPTLD IMRKPRCGVP DVGEYNVFPR TLKWSQTNLT
130 140 150 160 170 180
YRIVNYTPDM SHSEVEKAFR KAFKVWSDVT PLNFTRIYDG TADIMISFGT KEHGDFYPFD
190 200 210 220 230 240
GPSGLLAHAF PPGPNYGGDA HFDDDETWTS SSKGYNLFIV AAHELGHSLG LDHSKDPGAL
250 260 270 280 290 300
MFPIYTYTGK SHFMLPDDDV QGIQFLYGPG DEDPNPKHPK TPEKCDPALS LDAITSLRGE
310 320 330 340 350 360
TMIFKDRFFW RLHPQQVEAE LFLTKSFWPE LPNHVDAAYE HPSRDLMFIF RGRKFWALNG
370 380 390 400 410 420
YDILEGYPRK ISDLGFPKEV KRLSAAVHFE NTGKTLFFSE NHVWSYDDVN QTMDKDYPRL
430 440 450 460 470
IEEEFPGIGN KVDAVYEKNG YIYFFNGPIQ FEYSIWSNRI VRVMPTNSIL WC
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 4 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P33435-20-unknown | LPLPYG... | 20 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P33435-105-unknown | YNVFPR... | 105 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...SILWC | 472 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CXCL5_MOUSE | 44 | PSSV.|.VIAA | inferred from experiment | unknown | MEROPS | Overall CM | Tester AM et al.:LPS responsiveness and neutroph... (M10.013) | 17375198, |
CO1A1_MOUSE | 163 | SAGV.|.VSVP | inferred from experiment | unknown | MEROPS | Jaenisch R | Liu X et al.:A targeted mutation at the know... (M10.013) | 7790374, |
CO1A1-Isoform2_MOUSE | 163 | SAGV.|.VSVP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32749 | ||
LAMC2_MOUSE | 606 | HAAL.|.LTSC | inferred from experiment | unknown | MEROPS | Maisi P | Pirila E et al.:Matrix metalloproteinases proce... (M10.009) | 12684035, |