TopFIND 4.0

P34960: Macrophage metalloelastase

General Information

Protein names
- Macrophage metalloelastase
- MME
- 3.4.24.65
- Matrix metalloproteinase-12
- MMP-12
Gene names Mmp12
Organism Mus musculus
Protease Family M10.009
Protease ID M10.009
Chromosome location
UniProt ID P34960

5

N-termini

4

C-termini

2

Cleavages

55

Substrates

Sequence

        10         20         30         40         50         60 
MSCTLLKGVC TMKFLMMIVF LQVSACGAAP MNDSEFAEWY LSRFYDYGKD RIPMTKTKTN 
        70         80         90        100        110        120 
RNFLKEKLQE MQQFFGLEAT GQLDNSTLAI MHIPRCGVPD VQHLRAVPQR SRWMKRYLTY 
       130        140        150        160        170        180 
RIYNYTPDMK REDVDYIFQK AFQVWSDVTP LRFRKLHKDE ADIMILFAFG AHGDFNYFDG 
       190        200        210        220        230        240 
KGGTLAHAFY PGPGIQGDAH FDEAETWTKS FQGTNLFLVA VHELGHSLGL QHSNNPKSIM 
       250        260        270        280        290        300 
YPTYRYLNPS TFRLSADDIR NIQSLYGAPV KPPSLTKPSS PPSTFCHQSL SFDAVTTVGE 
       310        320        330        340        350        360 
KIFFFKDWFF WWKLPGSPAT NITSISSIWP SIPSGIQAAY EIESRNQLFL FKDEKYWLIN 
       370        380        390        400        410        420 
NLVPEPHYPR SIYSLGFSAS VKKVDAAVFD PLRQKVYFFV DKHYWRYDVR QELMDPAYPK 
       430        440        450        460        470    
LISTHFPGIK PKIDAVLYFK RHYYIFQGAY QLEYDPLFRR VTKTLKSTSW FGC

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 2 Cleavages - 55 Substrates

N-termini

C-termini

Cleavages

Substrates