P35456: Urokinase plasminogen activator surface receptor

General Information

Protein names	- Urokinase plasminogen activator surface receptor - U-PAR - uPAR - CD87
Gene names	Plaur
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P35456

5 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGLPRRLLLL LLLATTCVPA SQGLQCMQCE SNQSCLVEEC ALGQDLCRTT VLREWQDDRE
        70         80         90        100        110        120
LEVVTRGCAH SEKTNRTMSY RMGSMIISLT ETVCATNLCN RPRPGARGRA FPQGRYLECA
       130        140        150        160        170        180
SCTSLDQSCE RGREQSLQCR YPTEHCIEVV TLQSTERSLK DEDYTRGCGS LPGCPGTAGF
       190        200        210        220        230        240
HSNQTFHFLK CCNYTHCNGG PVLDLQSFPP NGFQCYSCEG NNTLGCSSEE ASLINCRGPM
       250        260        270        280        290        300
NQCLVATGLD VLGNRSYTVR GCATASWCQG SHVADSFPTH LNVSVSCCHG SGCNSPTGGA
       310        320
PRPGPAQLSL IASLLLTLGL WGVLLWT

Isoforms

- Isoform 2 of Urokinase plasminogen activator surface receptor

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P35456-1-unknown	MGLPRR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93934
P35456-24-unknown	LQCMQC...	24	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P35456-24-unknown	LQCMQC...	24	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113412
P35456-108-unknown	GRAFPQ...	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34819
P35456-108-unknown	GRAFPQ...	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34779
P35456-108-unknown	GRAFPQ...	108	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142791
P35456-110-unknown	AFPQGR...	110	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34781
P35456-110-unknown	AFPQGR...	110	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142966
P35456-113-unknown	QGRYLE...	113	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32745
P35456-113-unknown	QGRYLE...	113	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt143148

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RPGARG	107	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34819
...RPGARG	107	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34779
...RPGARG	107	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125996
...GARGRA	109	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34781
...GARGRA	109	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126175
...GRAFPQ	112	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32745
...GRAFPQ	112	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126370
...NSPTGG	298	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
UROK_MOUSE	107	GARG.\|.GRAF	inferred from experiment	unknown	MEROPS	Sidenius N	Andolfo A et al.:Metalloproteases cleave the uro... (S01.131)	12195704,
PLMN_MOUSE	107	GARG.\|.GRAF	inferred from experiment	unknown	MEROPS	Sidenius N	Andolfo A et al.:Metalloproteases cleave the uro... (S01.131)	12195704,
PLMN_MOUSE	109	RGRA.\|.AFPQ	inferred from experiment	unknown	MEROPS	Sidenius N	Andolfo A et al.:Metalloproteases cleave the uro... (S01.131)	12195704,
MMP12_MOUSE	112	AFPQ.\|.QGRY	inferred from experiment	unknown	MEROPS	Sidenius N	Andolfo A et al.:Metalloproteases cleave the uro... (S01.131)	12195704,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)