TopFIND 4.0

P06869: Urokinase-type plasminogen activator

General Information

Protein names
- Urokinase-type plasminogen activator
- U-plasminogen activator
- uPA
- 3.4.21.73
- Urokinase-type plasminogen activator long chain A
- Urokinase-type plasminogen activator short chain A
- Urokinase-type plasminogen activator chain B
Gene names Plau
Organism Mus musculus
Protease Family S01.231
Protease ID S01.231
Chromosome location
UniProt ID P06869

3

N-termini

2

C-termini

0

Cleavages

2

Substrates

Sequence

        10         20         30         40         50         60 
MKVWLASLFL CALVVKNSEG GSVLGAPDES NCGCQNGGVC VSYKYFSRIR RCSCPRKFQG 
        70         80         90        100        110        120 
EHCEIDASKT CYHGNGDSYR GKANTDTKGR PCLAWNAPAV LQKPYNAHRP DAISLGLGKH 
       130        140        150        160        170        180 
NYCRNPDNQK RPWCYVQIGL RQFVQECMVH DCSLSKKPSS SVDQQGFQCG QKALRPRFKI 
       190        200        210        220        230        240 
VGGEFTEVEN QPWFAAIYQK NKGGSPPSFK CGGSLISPCW VASAAHCFIQ LPKKENYVVY 
       250        260        270        280        290        300 
LGQSKESSYN PGEMKFEVEQ LILHEYYRED SLAYHNDIAL LKIRTSTGQC AQPSRSIQTI 
       310        320        330        340        350        360 
CLPPRFTDAP FGSDCEITGF GKESESDYLY PKNLKMSVVK LVSHEQCMQP HYYGSEINYK 
       370        380        390        400        410        420 
MLCAADPEWK TDSCKGDSGG PLICNIEGRP TLSGIVSWGR GCAEKNKPGV YTRVSHFLDW 
       430    
IQSHIGEEKG LAF

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 2 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P06869-21-unknown GSVLGA... 21 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P06869-157-unknown KPSSSV... 157 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P06869-180-unknown IVGGEF... 180 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LRPRFK 178 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...KGLAF 433 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates