TopFIND 4.0

O75844: CAAX prenyl protease 1 homolog

General Information

Protein names
- CAAX prenyl protease 1 homolog
- 3.4.24.84
- Farnesylated proteins-converting enzyme 1
- FACE-1
- Prenyl protein-specific endoprotease 1
- Zinc metalloproteinase Ste24 homolog
Gene names ZMPSTE24
Organism Homo sapiens
Protease Family M48.003
Protease ID M48.003
Chromosome location
UniProt ID O75844

1

N-termini

1

C-termini

0

Cleavages

4

Substrates

Sequence

        10         20         30         40         50         60 
MGMWASLDAL WEMPAEKRIF GAVLLFSWTV YLWETFLAQR QRRIYKTTTH VPPELGQIMD 
        70         80         90        100        110        120 
SETFEKSRLY QLDKSTFSFW SGLYSETEGT LILLFGGIPY LWRLSGRFCG YAGFGPEYEI 
       130        140        150        160        170        180 
TQSLVFLLLA TLFSALTGLP WSLYNTFVIE EKHGFNQQTL GFFMKDAIKK FVVTQCILLP 
       190        200        210        220        230        240 
VSSLLLYIIK IGGDYFFIYA WLFTLVVSLV LVTIYADYIA PLFDKFTPLP EGKLKEEIEV 
       250        260        270        280        290        300 
MAKSIDFPLT KVYVVEGSKR SSHSNAYFYG FFKNKRIVLF DTLLEEYSVL NKDIQEDSGM 
       310        320        330        340        350        360 
EPRNEEEGNS EEIKAKVKNK KQGCKNEEVL AVLGHELGHW KLGHTVKNII ISQMNSFLCF 
       370        380        390        400        410        420 
FLFAVLIGRK ELFAAFGFYD SQPTLIGLLI IFQFIFSPYN EVLSFCLTVL SRRFEFQADA 
       430        440        450        460        470    
FAKKLGKAKD LYSALIKLNK DNLGFPVSDW LFSMWHYSHP PLLERLQALK TMKQH

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 4 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O75844-1-unknown MGMWAS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TMKQH 475 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates