O75909: Cyclin-K

General Information

Protein names	- Cyclin-K
Gene names	CCNK
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75909

5 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Cyclin-K - Isoform 3 of Cyclin-K - Isoform 4 of Cyclin-K

Sequence View

        10         20         30         40         50         60
MKENKENSSP SVTSANLDHT KPCWYWDKKD LAHTPSQLEG LDPATEARYR REGARFIFDV
        70         80         90        100        110        120
GTRLGLHYDT LATGIIYFHR FYMFHSFKQF PRYVTGACCL FLAGKVEETP KKCKDIIKTA
       130        140        150        160        170        180
RSLLNDVQFG QFGDDPKEEV MVLERILLQT IKFDLQVEHP YQFLLKYAKQ LKGDKNKIQK
       190        200        210        220        230        240
LVQMAWTFVN DSLCTTLSLQ WEPEIIAVAV MYLAGRLCKF EIQEWTSKPM YRRWWEQFVQ
       250        260        270        280        290        300
DVPVDVLEDI CHQILDLYSQ GKQQMPHHTP HQLQQPPSLQ PTPQVPQVQQ SQPSQSSEPS
       310        320        330        340        350        360
QPQQKDPQQP AQQQQPAQQP KKPSPQPSSP RQVKRAVVVS PKEENKAAEP PPPKIPKIET
       370        380        390        400        410        420
THPPLPPAHP PPDRKPPLAA ALGEAEPPGP VDATDLPKVQ IPPPAHPAPV HQPPPLPHRP
       430        440        450        460        470        480
PPPPPSSYMT GMSTTSSYMS GEGYQSLQSM MKTEGPSYGA LPPAYGPPAH LPYHPHVYPP
       490        500        510        520        530        540
NPPPPPVPPP PASFPPPAIP PPTPGYPPPP PTYNPNFPPP PPRLPPTHAV PPHPPPGLGL
       550        560        570        580
PPASYPPPAV PPGGQPPVPP PIPPPGMPPV GGLGRAAWMR         10         20         30         40         50         60
MKENKENSSP SVTSANLDHT KPCWYWDKKD LAHTPSQLEG LDPATEARYR REGARFIFDV
        70         80         90        100        110        120
GTRLGLHYDT LATGIIYFHR FYMFHSFKQF PRYVTGACCL FLAGKVEETP KKCKDIIKTA
       130        140        150        160        170        180
RSLLNDVQFG QFGDDPKEEV MVLERILLQT IKFDLQVEHP YQFLLKYAKQ LKGDKNKIQK
       190        200        210        220        230        240
LVQMAWTFVN DSLCTTLSLQ WEPEIIAVAV MYLAGRLCKF EIQEWTSKPM YRRWWEQFVQ
       250        260        270        280        290        300
DVPVDVLEDI CHQILDLYSQ GKQQMPHHTP HQLQQPPSLQ PTPQVPQVQQ SQPSQSSEPS
       310        320        330        340        350        360
QPQQKDPQQP AQQQQPAQQP KKPSPQPSSP RQVKRAVVVS PKEENKAAEP PPPKIPKIET
       370        380        390        400        410        420
THPPLPPAHP PPDRKPPLAA ALGEAEPPGP VDATDLPKVQ IPPPAHPAPV HQPPPLPHRP
       430        440        450        460        470        480
PPPPPSSYMT GMSTTSSYMS GEGYQSLQSM MKTEGPSYGA LPPAYGPPAH LPYHPHVYPP
       490        500        510        520        530        540
NPPPPPVPPP PASFPPPAIP PPTPGYPPPP PTYNPNFPPP PPRLPPTHAV PPHPPPGLGL
       550        560        570        580
PPASYPPPAV PPGGQPPVPP PIPPPGMPPV GGLGRAAWMR         10         20         30         40         50         60
MKENKENSSP SVTSANLDHT KPCWYWDKKD LAHTPSQLEG LDPATEARYR REGARFIFDV
        70         80         90        100        110        120
GTRLGLHYDT LATGIIYFHR FYMFHSFKQF PRYVTGACCL FLAGKVEETP KKCKDIIKTA
       130        140        150        160        170        180
RSLLNDVQFG QFGDDPKEEV MVLERILLQT IKFDLQVEHP YQFLLKYAKQ LKGDKNKIQK
       190        200        210        220        230        240
LVQMAWTFVN DSLCTTLSLQ WEPEIIAVAV MYLAGRLCKF EIQEWTSKPM YRRWWEQFVQ
       250        260        270        280        290        300
DVPVDVLEDI CHQILDLYSQ GKQQMPHHTP HQLQQPPSLQ PTPQVPQVQQ SQPSQSSEPS
       310        320        330        340        350        360
QPQQKDPQQP AQQQQPAQQP KKPSPQPSSP RQVKRAVVVS PKEENKAAEP PPPKIPKIET
       370        380        390        400        410        420
THPPLPPAHP PPDRKPPLAA ALGEAEPPGP VDATDLPKVQ IPPPAHPAPV HQPPPLPHRP
       430        440        450        460        470        480
PPPPPSSYMT GMSTTSSYMS GEGYQSLQSM MKTEGPSYGA LPPAYGPPAH LPYHPHVYPP
       490        500        510        520        530        540
NPPPPPVPPP PASFPPPAIP PPTPGYPPPP PTYNPNFPPP PPRLPPTHAV PPHPPPGLGL
       550        560        570        580
PPASYPPPAV PPGGQPPVPP PIPPPGMPPV GGLGRAAWMR

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O75909-1-unknown	MKENKE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75909-1-unknown	MKENKE...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt69782
O75909-1-unknown	MKENKE...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt69784
O75909-381-	ALGEAE...	381		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O75909-381-unknown	ALGEAE...	381	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176419
O75909-383-	GEAEPP...	383		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O75909-383-unknown	GEAEPP...	383	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172665

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...AAWMR	580	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...AAWMR	580	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt65402

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)