O75937: DnaJ homolog subfamily C member 8

General Information

Protein names	- DnaJ homolog subfamily C member 8 - Splicing protein spf31
Gene names	DNAJC8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75937

6 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAASGESGTS GGGGSTEEAF MTFYSEVKQI EKRDSVLTSK NQIERLTRPG SSYFNLNPFE
        70         80         90        100        110        120
VLQIDPEVTD EEIKKRFRQL SILVHPDKNQ DDADRAQKAF EAVDKAYKLL LDQEQKKRAL
       130        140        150        160        170        180
DVIQAGKEYV EHTVKERKKQ LKKEGKPTIV EEDDPELFKQ AVYKQTMKLF AELEIKRKER
       190        200        210        220        230        240
EAKEMHERKR QREEEIEAQE KAKREREWQK NFEESRDGRV DSWRNFQANT KGKKEKKNRT
       250
FLRPPKVKME QRE

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O75937-2-unknown	MAASGE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75937-2-Acetylation	AASGES...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75937-2-Acetylation	AASGES...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O75937-18-unknown	EAFMTF...	18		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18322
O75937-21-unknown	MTFYSE...	21			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O75937-21-	MTFYSE...	21			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O75937-79-unknown	QLSILV...	79		inferred from electronic annotation	unknown	TISdb		inferred from TISdb

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GGSTEE	17	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18322
	...MEQRE	253	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	17	STEE.\|.EAFM	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)