O88947: Coagulation factor X

General Information

Protein names	- Coagulation factor X - 3.4.21.6 - Stuart factor - Factor X light chain - Factor X heavy chain - Activated factor Xa heavy chain
Gene names	F10
Organism	Mus musculus
Protease Family	S01.216
Protease ID	S01.216
Chromosome location
UniProt ID	O88947

4 N-termini

3 C-termini

0 Cleavages

3 Substrates

Sequence

        10         20         30         40         50         60
MGSPVQLSLL CVVLASLLLP GKGVFINRER ANNVLARTRR ANSFFEEFKK GNLERECMEE
        70         80         90        100        110        120
ICSYEEVREI FEDDEKTKEY WTKYKDGDQC ESSPCQNQGA CRDGIGGYTC TCSEGFEGKN
       130        140        150        160        170        180
CELFVRKLCR LDNGDCDQFC REEQNSVVCS CASGYFLGND GKSCISTAPF PCGKITTGRR
       190        200        210        220        230        240
KRSVALNTSD SELDLEDALL DEDFLSPTEN PIELLNLNET QPERSSDDLV RIVGGRECKD
       250        260        270        280        290        300
GECPWQALLI NEDNEGFCGG TILNEFYILT AAHCLHQARR FKVRVGDRNT EKEEGNEMVH
       310        320        330        340        350        360
EVDVVIKHNK FQRDTYDYDI AVLRLKTPIT FRMNVAPACL PQKDWAESTL MTQKTGIVSG
       370        380        390        400        410        420
FGRTHEKGRQ SNILKMLEVP YVDRNTCKLS TSFSITQNMF CAGYEAKLED ACQGDSGGPH
       430        440        450        460        470        480
VTRFKNTYYV TGIVSWGEGC ARKGKYGIYT KVTTFLKWID RSMKARVGPT AETPRTAGPP

N

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 3 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O88947-21-unknown	GKGVFI...	21	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O88947-41-unknown	ANSFFE...	41	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O88947-41-unknown	ANSFFE...	41	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
O88947-184-unknown	VALNTS...	184	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O88947-232-unknown	IVGGRE...	232	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O88947-232-unknown	IVGGRE...	232	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GFEGKN	119	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116984
...TTGRRK	180	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...AGPPN	481	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
THRB_MOUSE	108	EGRC.\|.CAMD	inferred from experiment	unknown	MEROPS	Engh RA	Brandstetter H et al.:X-ray structure of active site-... (S01.216)	8939944,
THRB_MOUSE	324	NEKT.\|.TFGL	inferred from experiment	unknown	MEROPS		Merops FA10_MOUSE -> THRB_MOUSE @324
THRB_MOUSE	360	DGRI.\|.IVEG	inferred from experiment	unknown	MEROPS		Merops FA10_MOUSE -> THRB_MOUSE @360