TopFIND 4.0

O89094: Caspase-14

General Information

Protein names
- Caspase-14
- CASP-14
- 3.4.22.-
- Mini-ICE
- MICE
- Caspase-14 subunit p17, mature form
- Caspase-14 subunit p10, mature form
- Caspase-14 subunit p20, intermediate form
- Caspase-14 subunit p8, intermediate form
Gene names Casp14
Organism Mus musculus
Protease Family C14.018
Protease ID C14.018
Chromosome location
UniProt ID O89094

3

N-termini

2

C-termini

0

Cleavages

1

Substrates

Sequence

        10         20         30         40         50         60 
MESEMSDPQP LQEERYDMSG ARLALTLCVT KAREGSEVDM EALERMFRYL KFESTMKRDP 
        70         80         90        100        110        120 
TAQQFLEELD EFQQTIDNWE EPVSCAFVVL MAHGEEGLLK GEDEKMVRLE DLFEVLNNKN 
       130        140        150        160        170        180 
CKALRGKPKV YIIQACRGEH RDPGEELRGN EELGGDEELG GDEVAVLKNN PQSIPTYTDT 
       190        200        210        220        230        240 
LHIYSTVEGY LSYRHDEKGS GFIQTLTDVF IHKKGSILEL TEEITRLMAN TEVMQEGKPR 
       250    
KVNPEVQSTL RKKLYLQ

Isoforms

- Isoform 2 of Caspase-14

Sequence View

        10         20         30         40         50         60 
MESEMSDPQP LQEERYDMSG ARLALTLCVT KAREGSEVDM EALERMFRYL KFESTMKRDP 
        70         80         90        100        110        120 
TAQQFLEELD EFQQTIDNWE EPVSCAFVVL MAHGEEGLLK GEDEKMVRLE DLFEVLNNKN 
       130        140        150        160        170        180 
CKALRGKPKV YIIQACRGEH RDPGEELRGN EELGGDEELG GDEVAVLKNN PQSIPTYTDT 
       190        200        210        220        230        240 
LHIYSTVEGY LSYRHDEKGS GFIQTLTDVF IHKKGSILEL TEEITRLMAN TEVMQEGKPR 
       250    
KVNPEVQSTL RKKLYLQ



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Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 1 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EVAVLK 167 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...KLYLQ 257 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates