TopFIND 4.0

P70444: BH3-interacting domain death agonist

General Information

Protein names	- BH3-interacting domain death agonist - p22 BID - BID - BH3-interacting domain death agonist p15 - p15 BID - BH3-interacting domain death agonist p13 - p13 BID - BH3-interacting domain death agonist p11 - p11 BID
Gene names	Bid
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P70444

11 N-termini

9 C-termini

13 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDSEVSNGSG LGAEHITDLL VFGFLQSSGC TRQELEVLGR ELPVQAYWEA DLEDELQTDG
        70         80         90        100        110        120
SQASRSFNQG RIEPDSESQE EIIHNIARHL AQIGDEMDHN IQPTLVRQLA AQFMNGSLSE
       130        140        150        160        170        180
EDKRNCLAKA LDEVKTAFPR DMENDKAMLI MTMLLAKKVA SHAPSLLRDV FHTTVNFINQ
       190
NLFSYVRNLV RNEMD

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

11 N-termini - 9 C-termini - 13 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P70444-1-Acetylation	MDSEVS...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P70444-7-unknown	NGSGLG...	7		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31404
P70444-13-unknown	AEHITD...	13		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31405
P70444-13-unknown	AEHITD...	13		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31408
P70444-13-unknown	AEHITD...	13		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31426
P70444-48-unknown	WEADLE...	48		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31406
P70444-48-unknown	WEADLE...	48		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31427
P70444-58-unknown	TDGSQA...	58		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31428
P70444-60-unknown	GSQASR...	60		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28609
P70444-60-unknown	GSQASR...	60		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28621
P70444-61-unknown	SQASRS...	61		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P70444-66-unknown	SFNQGR...	66		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31409
P70444-66-unknown	SFNQGR...	66		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31423
P70444-66-unknown	SFNQGR...	66		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31429
P70444-72-unknown	IEPDSE...	72		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31407
P70444-76-unknown	SESQEE...	76		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P70444-99-unknown	HNIQPT...	99		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DSEVSN	6	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31404
...GSGLGA	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31405
...GSGLGA	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31408
...GSGLGA	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31426
...PVQAYW	47	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31406
...PVQAYW	47	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31427
...WEADLE	52	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117529
...EDELQT	57	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31428
...ELQTDG	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28609
...ELQTDG	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28621
...SQASRS	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31409
...SQASRS	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31423
...SQASRS	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31429
...FNQGRI	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31407
...RNEMD	195	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATH_MOUSE	6	EVSN.\|.NGSG	inferred from experiment	unknown	MEROPS	Turk B	Cirman T et al.:Selective disruption of lysosom... (C01.040)	14581476,
CATH_MOUSE	12	GLGA.\|.AEHI	inferred from experiment	unknown	MEROPS	Turk B	Cirman T et al.:Selective disruption of lysosom... (C01.040)	14581476,
CATK_MOUSE	12	GLGA.\|.AEHI	inferred from experiment	unknown	MEROPS	Turk B	Cirman T et al.:Selective disruption of lysosom... (C01.040)	14581476,
CATS_MOUSE	12	GLGA.\|.AEHI	inferred from experiment	unknown	MEROPS	Turk B	Cirman T et al.:Selective disruption of lysosom... (C01.040)	14581476,
CATH_MOUSE	47	QAYW.\|.WEAD	inferred from experiment	unknown	MEROPS	Turk B	Cirman T et al.:Selective disruption of lysosom... (C01.040)	14581476,
CATS_MOUSE	47	QAYW.\|.WEAD	inferred from experiment	unknown	MEROPS	Turk B	Cirman T et al.:Selective disruption of lysosom... (C01.040)	14581476,
CATS_MOUSE	57	ELQT.\|.TDGS	inferred from experiment	unknown	MEROPS	Turk B	Cirman T et al.:Selective disruption of lysosom... (C01.040)	14581476,
CASP8_MOUSE	59	QTDG.\|.GSQA	inferred from experiment	unknown	MEROPS	Salvesen GS	Stoka V et al.:Lysosomal protease pathways to ... (C14.009)	11073962,
CASPE_MOUSE	59	QTDG.\|.GSQA	inferred from experiment	unknown	MEROPS	Salvesen GS	Mikolajczyk J et al.:Activation and substrate specif... (C14.018)	15301553,
CATK_MOUSE	65	ASRS.\|.SFNQ	inferred from experiment	unknown	MEROPS	Turk B	Cirman T et al.:Selective disruption of lysosom... (C01.040)	14581476,
CATL1_MOUSE	65	ASRS.\|.SFNQ	inferred from experiment	unknown	MEROPS	Turk B	Cirman T et al.:Selective disruption of lysosom... (C01.040)	14581476,
CATS_MOUSE	65	ASRS.\|.SFNQ	inferred from experiment	unknown	MEROPS	Turk B	Cirman T et al.:Selective disruption of lysosom... (C01.040)	14581476,
CATH_MOUSE	71	QGRI.\|.IEPD	inferred from experiment	unknown	MEROPS	Turk B	Cirman T et al.:Selective disruption of lysosom... (C01.040)	14581476,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)