TopFIND 4.0

O89110: Caspase-8

General Information

Protein names
- Caspase-8
- CASP-8
- 3.4.22.61
- Caspase-8 subunit p18
- Caspase-8 subunit p10
Gene names Casp8
Organism Mus musculus
Protease Family C14.009
Protease ID C14.009
Chromosome location
UniProt ID O89110

2

N-termini

2

C-termini

0

Cleavages

12

Substrates

Sequence

        10         20         30         40         50         60 
MDFQSCLYAI AEELGSEDLA ALKFLCLDYI PHKKQETIED AQKLFLRLRE KGMLEEGNLS 
        70         80         90        100        110        120 
FLKELLFHIS RWDLLVNFLD CNREEMVREL RDPDNAQISP YRVMLFKLSE EVSELELRSF 
       130        140        150        160        170        180 
KFLLNNEIPK CKLEDDLSLL EIFVEMEKRT MLAENNLETL KSICDQVNKS LLGKIEDYER 
       190        200        210        220        230        240 
SSTERRMSLE GREELPPSVL DEMSLKMAEL CDSPREQDSE SRTSDKVYQM KNKPRGYCLI 
       250        260        270        280        290        300 
INNHDFSKAR EDITQLRKMK DRKGTDCDKE ALSKTFKELH FEIVSYDDCT ANEIHEILEG 
       310        320        330        340        350        360 
YQSADHKNKD CFICCILSHG DKGVVYGTDG KEASIYDLTS YFTGSKCPSL SGKPKIFFIQ 
       370        380        390        400        410        420 
ACQGSNFQKG VPDEAGFEQQ NHTLEVDSSS HKNYIPDEAD FLLGMATVKN CVSYRDPVNG 
       430        440        450        460        470        480 
TWYIQSLCQS LRERCPQGDD ILSILTGVNY DVSNKDDRRN KGKQMPQPTF TLRKKLFFPP 
   

Isoforms



Sequence View



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(REFRESH)

Directness:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 12 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PDEAGF 376 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LFFPP 480 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates