O94760: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

General Information

Protein names	- N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 - DDAH-1 - Dimethylarginine dimethylaminohydrolase 1 - 3.5.3.18 - DDAHI - Dimethylargininase-1
Gene names	DDAH1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O94760

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGLGHPAAF GRATHAVVRA LPESLGQHAL RSAKGEEVDV ARAERQHQLY VGVLGSKLGL
        70         80         90        100        110        120
QVVELPADES LPDCVFVEDV AVVCEETALI TRPGAPSRRK EVDMMKEALE KLQLNIVEMK
       130        140        150        160        170        180
DENATLDGGD VLFTGREFFV GLSKRTNQRG AEILADTFKD YAVSTVPVAD GLHLKSFCSM
       190        200        210        220        230        240
AGPNLIAIGS SESAQKALKI MQQMSDHRYD KLTVPDDIAA NCIYLNIPNK GHVLLHRTPE
       250        260        270        280
EYPESAKVYE KLKDHMLIPV SMSELEKVDG LLTCCSVLIN KKVDS

Isoforms

- Isoform 2 of N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

Sequence View

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
O94760-2-unknown	MAGLGH...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O94760-2-Acetylation	AGLGHP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O94760-104-unknown	MMKEAL...	104		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt72504
O94760-165-unknown	TVPVAD...	165		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5278
O94760-165-unknown	TVPVAD...	165		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140106

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DYAVST	164	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5278
...DYAVST	164	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123214
...KKVDS	285	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KKVDS	285	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68122

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	164	AVST.\|.TVPV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

O94760: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

General Information

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates