TopFIND 4.0

O95674: Phosphatidate cytidylyltransferase 2

General Information

Protein names
- Phosphatidate cytidylyltransferase 2
- 2.7.7.41
- CDP-DAG synthase 2
- CDP-DG synthase 2
- CDP-diacylglycerol synthase 2
- CDS 2
- CDP-diglyceride pyrophosphorylase 2
- CDP-diglyceride synthase 2
- CTP:phosphatidate cytidylyltransferase 2
Gene names CDS2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O95674

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTELRQRVAH EPVAPPEDKE SESEAKVDGE TASDSESRAE SAPLPVSADD TPEVLNRALS 
        70         80         90        100        110        120 
NLSSRWKNWW VRGILTLAMI AFFFIIIYLG PMVLMIIVMC VQIKCFHEII TIGYNVYHSY 
       130        140        150        160        170        180 
DLPWFRTLSW YFLLCVNYFF YGETVTDYFF TLVQREEPLR ILSKYHRFIS FTLYLIGFCM 
       190        200        210        220        230        240 
FVLSLVKKHY RLQFYMFGWT HVTLLIVVTQ SHLVIHNLFE GMIWFIVPIS CVICNDIMAY 
       250        260        270        280        290        300 
MFGFFFGRTP LIKLSPKKTW EGFIGGFFAT VVFGLLLSYV MSGYRCFVCP VEYNNDTNSF 
       310        320        330        340        350        360 
TVDCEPSDLF RLQEYNIPGV IQSVIGWKTV RMYPFQIHSI ALSTFASLIG PFGGFFASGF 
       370        380        390        400        410        420 
KRAFKIKDFA NTIPGHGGIM DRFDCQYLMA TFVNVYIASF IRGPNPSKLI QQFLTLRPDQ 
       430        440    
QLHIFNTLRS HLIDKGMLTS TTEDE

Isoforms

- Isoform 2 of Phosphatidate cytidylyltransferase 2

Sequence View

        10         20         30         40         50         60 
MTELRQRVAH EPVAPPEDKE SESEAKVDGE TASDSESRAE SAPLPVSADD TPEVLNRALS 
        70         80         90        100        110        120 
NLSSRWKNWW VRGILTLAMI AFFFIIIYLG PMVLMIIVMC VQIKCFHEII TIGYNVYHSY 
       130        140        150        160        170        180 
DLPWFRTLSW YFLLCVNYFF YGETVTDYFF TLVQREEPLR ILSKYHRFIS FTLYLIGFCM 
       190        200        210        220        230        240 
FVLSLVKKHY RLQFYMFGWT HVTLLIVVTQ SHLVIHNLFE GMIWFIVPIS CVICNDIMAY 
       250        260        270        280        290        300 
MFGFFFGRTP LIKLSPKKTW EGFIGGFFAT VVFGLLLSYV MSGYRCFVCP VEYNNDTNSF 
       310        320        330        340        350        360 
TVDCEPSDLF RLQEYNIPGV IQSVIGWKTV RMYPFQIHSI ALSTFASLIG PFGGFFASGF 
       370        380        390        400        410        420 
KRAFKIKDFA NTIPGHGGIM DRFDCQYLMA TFVNVYIASF IRGPNPSKLI QQFLTLRPDQ 
       430        440    
QLHIFNTLRS HLIDKGMLTS TTEDE



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O95674-1-unknown MTELRQ... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O95674-29- GETASD... 29 Subtiligase Based Positive Selection Wells apoptotic_MM1SDBJurkat_Mix 23264352

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TVDCEP 305 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt65769
    ...TTEDE 445 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)