O95749: Geranylgeranyl pyrophosphate synthase

General Information

Protein names	- Geranylgeranyl pyrophosphate synthase - GGPP synthase - GGPPSase - 2.5.1.- - (2E,6E)-farnesyl diphosphate synthase - Dimethylallyltranstransferase - 2.5.1.1 - Farnesyl diphosphate synthase - Farnesyltranstransferase - 2.5.1.29 - Geranylgeranyl diphosphate synthase - Geranyltranstransferase - 2.5.1.10
Gene names	GGPS1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95749

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEKTQETVQR ILLEPYKYLL QLPGKQVRTK LSQAFNHWLK VPEDKLQIII EVTEMLHNAS
        70         80         90        100        110        120
LLIDDIEDNS KLRRGFPVAH SIYGIPSVIN SANYVYFLGL EKVLTLDHPD AVKLFTRQLL
       130        140        150        160        170        180
ELHQGQGLDI YWRDNYTCPT EEEYKAMVLQ KTGGLFGLAV GLMQLFSDYK EDLKPLLNTL
       190        200        210        220        230        240
GLFFQIRDDY ANLHSKEYSE NKSFCEDLTE GKFSFPTIHA IWSRPESTQV QNILRQRTEN
       250        260        270        280        290        300
IDIKKYCVHY LEDVGSFEYT RNTLKELEAK AYKQIDARGG NPELVALVKH LSKMFKEENE

Isoforms

- Isoform 2 of Geranylgeranyl pyrophosphate synthase

Sequence View

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Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O95749-1-Acetylation	MEKTQE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95749-1-Acetylation	MEKTQE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O95749-1-Acetylation	MEKTQE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O95749-1-Acetylation	MEKTQE...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O95749-55-unknown	MLHNAS...	55		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000375728

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ESTQVQ	230	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417865
...TENIDI	242	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417772
...KEENE	300	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)