O95817: BAG family molecular chaperone regulator 3

General Information

Protein names	- BAG family molecular chaperone regulator 3 - BAG-3 - Bcl-2-associated athanogene 3 - Bcl-2-binding protein Bis - Docking protein CAIR-1
Gene names	BAG3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95817

10 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSAATHSPMM QVASGNGDRD PLPPGWEIKI DPQTGWPFFV DHNSRTTTWN DPRVPSEGPK
        70         80         90        100        110        120
ETPSSANGPS REGSRLPPAR EGHPVYPQLR PGYIPIPVLH EGAENRQVHP FHVYPQPGMQ
       130        140        150        160        170        180
RFRTEAAAAA PQRSQSPLRG MPETTQPDKQ CGQVAAAAAA QPPASHGPER SQSPAASDCS
       190        200        210        220        230        240
SSSSSASLPS SGRSSLGSHQ LPRGYISIPV IHEQNVTRPA AQPSFHQAQK THYPAQQGEY
       250        260        270        280        290        300
QTHQPVYHKI QGDDWEPRPL RAASPFRSSV QGASSREGSP ARSSTPLHSP SPIRVHTVVD
       310        320        330        340        350        360
RPQQPMTHRE TAPVSQPENK PESKPGPVGP ELPPGHIPIQ VIRKEVDSKP VSQKPPPPSE
       370        380        390        400        410        420
KVEVKVPPAP VPCPPPSPGP SAVPSSPKSV ATEERAAPST APAEATPPKP GEAEAPPKHP
       430        440        450        460        470        480
GVLKVEAILE KVQGLEQAVD NFEGKKTDKK YLMIEEYLTK ELLALDSVDP EGRADVRQAR
       490        500        510        520        530        540
RDGVRKVQTI LEKLEQKAID VPGQVQVYEL QPSNLEADQP LQAIMEMGAV AADKGKKNAG
       550        560        570
NAEDPHTETQ QPEATAAATS NPSSMTDTPG NPAAP

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

10 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O95817-2-unknown	MSAATH...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95817-2-Acetylation	SAATHS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95817-140-	GMPETT...	140			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O95817-152-	GQVAAA...	152			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
O95817-152-	GQVAAA...	152			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O95817-152-	GQVAAA...	152			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O95817-152-	GQVAAA...	152			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O95817-155-	AAAAAA...	155			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O95817-156-	AAAAAQ...	156			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O95817-156-	AAAAAQ...	156			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O95817-156-	AAAAAQ...	156			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O95817-158-	AAAQPP...	158			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O95817-159-	AAQPPA...	159			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
O95817-159-	AAQPPA...	159			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O95817-160-	AQPPAS...	160			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O95817-523-	AIMEMG...	523			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O95817-523-	AIMEMG...	523			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...PSAVPS	384	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000410036
	...NPAAP	575	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)