O95822: Malonyl-CoA decarboxylase, mitochondrial

General Information

Protein names	- Malonyl-CoA decarboxylase, mitochondrial - MCD - 4.1.1.9
Gene names	MLYCD
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95822

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRGFGPGLTA RRLLPLRLPP RPPGPRLASG QAAGALERAM DELLRRAVPP TPAYELREKT
        70         80         90        100        110        120
PAPAEGQCAD FVSFYGGLAE TAQRAELLGR LARGFGVDHG QVAEQSAGVL HLRQQQREAA
       130        140        150        160        170        180
VLLQAEDRLR YALVPRYRGL FHHISKLDGG VRFLVQLRAD LLEAQALKLV EGPDVREMNG
       190        200        210        220        230        240
VLKGMLSEWF SSGFLNLERV TWHSPCEVLQ KISEAEAVHP VKNWMDMKRR VGPYRRCYFF
       250        260        270        280        290        300
SHCSTPGEPL VVLHVALTGD ISSNIQAIVK EHPPSETEEK NKITAAIFYS ISLTQQGLQG
       310        320        330        340        350        360
VELGTFLIKR VVKELQREFP HLGVFSSLSP IPGFTKWLLG LLNSQTKEHG RNELFTDSEC
       370        380        390        400        410        420
KEISEITGGP INETLKLLLS SSEWVQSEKL VRALQTPLMR LCAWYLYGEK HRGYALNPVA
       430        440        450        460        470        480
NFHLQNGAVL WRINWMADVS LRGITGSCGL MANYRYFLEE TGPNSTSYLG SKIIKASEQV
       490
LSLVAQFQKN SKL

Isoforms

- Isoform Cytoplasmic+peroxisomal of Malonyl-CoA decarboxylase, mitochondrial

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O95822-0-unknown	LMRGFG...	0	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95822-28-unknown	ASGQAA...	28		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O95822-28-	ASGQAA...	28		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
O95822-28-	ASGQAA...	28		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
O95822-28-	ASGQAA...	28		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O95822-28-	ASGQAA...	28		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O95822-28-	ASGQAA...	28		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O95822-28-	ASGQAA...	28		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O95822-28-	ASGQAA...	28		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
O95822-40-unknown	MDELLR...	40	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt72455
O95822-40-unknown	MDELLR...	40	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...KNSKL	493	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...KNSKL	493	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt68073

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)