O95983: Methyl-CpG-binding domain protein 3

General Information

Protein names	- Methyl-CpG-binding domain protein 3 - Methyl-CpG-binding protein MBD3
Gene names	MBD3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95983

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MERKRWECPA LPQGWEREEV PRRSGLSAGH RDVFYYSPSG KKFRSKPQLA RYLGGSMDLS
        70         80         90        100        110        120
TFDFRTGKML MSKMNKSRQR VRYDSSNQVK GKPDLNTALP VRQTASIFKQ PVTKITNHPS
       130        140        150        160        170        180
NKVKSDPQKA VDQPRQLFWE KKLSGLNAFD IAEELVKTMD LPKGLQGVGP GCTDETLLSA
       190        200        210        220        230        240
IASALHTSTM PITGQLSAAV EKNPGVWLNT TQPLCKAFMV TDEDIRKQEE LVQQVRKRLE
       250        260        270        280        290
EALMADMLAH VEELARDGEA PLDKACAEDD DEEDEEEEEE EPDPDPEMEH V

Isoforms

- Isoform 2 of Methyl-CpG-binding domain protein 3

Sequence View

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O95983-1-unknown	MERKRW...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O95983-250-unknown	HVEELA...	250	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5301
O95983-250-unknown	HVEELA...	250	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt147279

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ADMLAH	249	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5301
...ADMLAH	249	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130622
...EMEHV	291	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EMEHV	291	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76140

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	249	MLAH.\|.HVEE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

O95983: Methyl-CpG-binding domain protein 3

General Information

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates