TopFIND 4.0

P00746: Complement factor D

General Information

Protein names
- Complement factor D
- 3.4.21.46
- Adipsin
- C3 convertase activator
- Properdin factor D
Gene names CFD
Organism Homo sapiens
Protease Family S01.191
Protease ID S01.191
Chromosome location
UniProt ID P00746

3

N-termini

1

C-termini

0

Cleavages

2

Substrates

Sequence

        10         20         30         40         50         60 
MHSWERLAVL VLLGAAACAA PPRGRILGGR EAEAHARPYM ASVQLNGAHL CGGVLVAEQW 
        70         80         90        100        110        120 
VLSAAHCLED AADGKVQVLL GAHSLSQPEP SKRLYDVLRA VPHPDSQPDT IDHDLLLLQL 
       130        140        150        160        170        180 
SEKATLGPAV RPLPWQRVDR DVAPGTLCDV AGWGIVNHAG RRPDSLQHVL LPVLDRATCN 
       190        200        210        220        230        240 
RRTHHDGAIT ERLMCAESNR RDSCKGDSGG PLVCGGVLEG VVTSGSRVCG NRKKPGIYTR 
       250    
VASYAAWIDS VLA

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 2 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DSVLA 253 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates