TopFIND 4.0

P02655: Apolipoprotein C-II

General Information

Protein names	- Apolipoprotein C-II - Apo-CII - ApoC-II - Apolipoprotein C2 - Proapolipoprotein C-II - ProapoC-II
Gene names	APOC2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P02655

4

N-termini

4

C-termini

3

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MGTRLLPALF LVLLVLGFEV QGTQQPQQDE MPSPTFLTQV KESLSSYWES AKTAAQNLYE
70 80 90 100
KTYLPAVDEK LRDLYSKSTA AMSTYTGIFT DQVLSVLKGE E

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P02655-23-unknown	TQQPQQ...	23		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P02655-37-unknown	LTQVKE...	37		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23975
P02655-58-unknown	LYEKTY...	58		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23976
P02655-58-unknown	LYEKTY...	58		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21455
P02655-88-	IFTDQV...	88			Subtiligase Based Positive Selection		Wells	THP_untreated	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...PSPTFL	36	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23975
	...TAAQNL	57	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23976
	...TAAQNL	57	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21455
	...DEKLRD	72	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000465001
	...LKGEE	101	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP7_HUMAN	36	PTFL.\|.LTQV	inferred from experiment	unknown	MEROPS	Lee ST	Kim SY et al.:Apolipoprotein C-II is a novel ... (M10.014)	16314153,
MMP7_HUMAN	57	AQNL.\|.LYEK	inferred from experiment	unknown	MEROPS	Lee ST	Kim SY et al.:Apolipoprotein C-II is a novel ... (M10.014)	16314153,
MMP14_HUMAN	57	AQNL.\|.LYEK	inferred from experiment	unknown	MEROPS	Lee ST	Kim SY et al.:Apolipoprotein C-II is a novel ... (M10.014)	16314153,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)