P06734: Low affinity immunoglobulin epsilon Fc receptor

General Information

Protein names	- Low affinity immunoglobulin epsilon Fc receptor - BLAST-2 - C-type lectin domain family 4 member J - Fc-epsilon-RII - Immunoglobulin E-binding factor - Lymphocyte IgE receptor - CD23 - Low affinity immunoglobulin epsilon Fc receptor membrane-bound form - Low affinity immunoglobulin epsilon Fc receptor soluble form
Gene names	FCER2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P06734

7 N-termini

6 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEEGQYSEIE ELPRRRCCRR GTQIVLLGLV TAALWAGLLT LLLLWHWDTT QSLKQLEERA
        70         80         90        100        110        120
ARNVSQVSKN LESHHGDQMA QKSQSTQISQ ELEELRAEQQ RLKSQDLELS WNLNGLQADL
       130        140        150        160        170        180
SSFKSQELNE RNEASDLLER LREEVTKLRM ELQVSSGFVC NTCPEKWINF QRKCYYFGKG
       190        200        210        220        230        240
TKQWVHARYA CDDMEGQLVS IHSPEEQDFL TKHASHTGSW IGLRNLDLKG EFIWVDGSHV
       250        260        270        280        290        300
DYSNWAPGEP TSRSQGEDCV MMRGSGRWND AFCDRKLGAW VCDRLATCTP PASEGSAESM
       310        320
GPDSRPDPDG RLPTPSAPLH S

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

7 N-termini - 6 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P06734-1-unknown	MEEGQY...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P06734-44-	LWHWDT...	44		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P06734-81-unknown	QKSQST...	81	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC95
P06734-81-unknown	QKSQST...	81	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC208
P06734-99-unknown	QQRLKS...	99	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC209
P06734-100-unknown	QRLKSQ...	100	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC96
P06734-100-unknown	QRLKSQ...	100	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC210
P06734-102-unknown	LKSQDL...	102	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC97
P06734-150-unknown	MELQVS...	150	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GDQMAQ	80	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC95
...GDQMAQ	80	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC208
...ELRAEQ	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC209
...LRAEQQ	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC96
...LRAEQQ	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC210
...AEQQRL	101	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC97
...YFGKGT	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472067
...APLHS	321	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
ADA10_HUMAN	80	QMAQ.\|.QKSQ	inferred from experiment	unknown	MEROPS	Werb Z	Lemieux GA et al.:The low affinity IgE receptor (... (M12.210)	17389606,
ADAM8_HUMAN	80	QMAQ.\|.QKSQ	inferred from experiment	unknown	MEROPS	Werb Z	Lemieux GA et al.:The low affinity IgE receptor (... (M12.210)	17389606,
ADAM8_HUMAN	98	RAEQ.\|.QQRL	inferred from experiment	unknown	MEROPS	Werb Z	Lemieux GA et al.:The low affinity IgE receptor (... (M12.210)	17389606,
ADA10_HUMAN	99	AEQQ.\|.QRLK	inferred from experiment	unknown	MEROPS	Werb Z	Lemieux GA et al.:The low affinity IgE receptor (... (M12.210)	17389606,
ADAM8_HUMAN	99	AEQQ.\|.QRLK	inferred from experiment	unknown	MEROPS	Werb Z	Lemieux GA et al.:The low affinity IgE receptor (... (M12.210)	17389606,
ADA10_HUMAN	101	QQRL.\|.LKSQ	inferred from experiment	unknown	MEROPS	Werb Z	Lemieux GA et al.:The low affinity IgE receptor (... (M12.210)	17389606,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)