P06745: Glucose-6-phosphate isomerase

General Information

Protein names	- Glucose-6-phosphate isomerase - GPI - 5.3.1.9 - Autocrine motility factor - AMF - Neuroleukin - NLK - Phosphoglucose isomerase - PGI - Phosphohexose isomerase - PHI
Gene names	Gpi
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P06745

16 N-termini

15 C-termini

19 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAALTRNPQF QKLLEWHRAN SANLKLRELF EADPERFNNF SLNLNTNHGH ILVDYSKNLV
        70         80         90        100        110        120
NKEVMQMLVE LAKSRGVEAA RDNMFSGSKI NYTENRAVLH VALRNRSNTP IKVDGKDVMP
       130        140        150        160        170        180
EVNRVLDKMK SFCQRVRSGD WKGYTGKSIT DIINIGIGGS DLGPLMVTEA LKPYSKGGPR
       190        200        210        220        230        240
VWFVSNIDGT HIAKTLASLS PETSLFIIAS KTFTTQETIT NAETAKEWFL EAAKDPSAVA
       250        260        270        280        290        300
KHFVALSTNT AKVKEFGIDP QNMFEFWDWV GGRYSLWSAI GLSIALHVGF DHFEQLLSGA
       310        320        330        340        350        360
HWMDQHFLKT PLEKNAPVLL ALLGIWYINC YGCETHALLP YDQYMHRFAA YFQQGDMESN
       370        380        390        400        410        420
GKYITKSGAR VDHQTGPIVW GEPGTNGQHA FYQLIHQGTK MIPCDFLIPV QTQHPIRKGL
       430        440        450        460        470        480
HHKILLANFL AQTEALMKGK LPEEARKELQ AAGKSPEDLE KLLPHKVFEG NRPTNSIVFT
       490        500        510        520        530        540
KLTPFILGAL IAMYEHKIFV QGIMWDINSF DQWGVELGKQ LAKKIEPELE GSSAVTSHDS
       550
STNGLISFIK QQRDTKLE

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

16 N-termini - 15 C-termini - 19 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P06745-2-unknown	MAALTR...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P06745-2-unknown	MAALTR...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P06745-2-Acetylation	AALTRN...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P06745-2-Acetylation	AALTRN...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P06745-67-unknown	MLVELA...	67		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29632
P06745-68-unknown	LVELAK...	68		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29633
P06745-69-unknown	VELAKS...	69		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28709
P06745-69-unknown	VELAKS...	69		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29634
P06745-169-unknown	EALKPY...	169		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28710
P06745-170-unknown	ALKPYS...	170		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28711
P06745-352-unknown	FQQGDM...	352		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28712
P06745-352-unknown	FQQGDM...	352		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29635
P06745-407-unknown	LIPVQT...	407		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29636
P06745-430-unknown	LAQTEA...	430		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28713
P06745-430-unknown	LAQTEA...	430		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29637
P06745-431-unknown	AQTEAL...	431		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28714
P06745-431-unknown	AQTEAL...	431		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29638
P06745-433-unknown	TEALMK...	433		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28715
P06745-434-unknown	EALMKG...	434		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28716
P06745-436-unknown	LMKGKL...	436		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29639
P06745-437-unknown	MKGKLP...	437		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28717
P06745-437-unknown	MKGKLP...	437		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29640
P06745-546-unknown	ISFIKQ...	546		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29641

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KEVMQM	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29632
...EVMQML	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29633
...VMQMLV	68	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28709
...VMQMLV	68	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29634
...PLMVTE	168	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28710
...LMVTEA	169	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28711
...RFAAYF	351	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28712
...RFAAYF	351	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29635
...IPCDFL	406	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29636
...LLANFL	429	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28713
...LLANFL	429	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29637
...LANFLA	430	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28714
...LANFLA	430	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29638
...NFLAQT	432	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28715
...FLAQTE	433	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28716
...AQTEAL	435	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29639
...QTEALM	436	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28717
...QTEALM	436	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29640
...STNGLI	545	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29641
...DTKLE	558	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	66	VMQM.\|.MLVE	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> G6PI_MOUSE @66
CATE_MOUSE	67	MQML.\|.LVEL	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> G6PI_MOUSE @67
CATD_MOUSE	68	QMLV.\|.VELA	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> G6PI_MOUSE @68
CATE_MOUSE	68	QMLV.\|.VELA	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> G6PI_MOUSE @68
CATD_MOUSE	168	MVTE.\|.EALK	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> G6PI_MOUSE @168
CATD_MOUSE	169	VTEA.\|.ALKP	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> G6PI_MOUSE @169
CATD_MOUSE	351	AAYF.\|.FQQG	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> G6PI_MOUSE @351
CATE_MOUSE	351	AAYF.\|.FQQG	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> G6PI_MOUSE @351
CATE_MOUSE	406	CDFL.\|.LIPV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> G6PI_MOUSE @406
CATD_MOUSE	429	ANFL.\|.LAQT	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> G6PI_MOUSE @429
CATE_MOUSE	429	ANFL.\|.LAQT	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> G6PI_MOUSE @429
CATD_MOUSE	430	NFLA.\|.AQTE	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> G6PI_MOUSE @430
CATE_MOUSE	430	NFLA.\|.AQTE	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> G6PI_MOUSE @430
CATD_MOUSE	432	LAQT.\|.TEAL	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> G6PI_MOUSE @432
CATD_MOUSE	433	AQTE.\|.EALM	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> G6PI_MOUSE @433
CATE_MOUSE	435	TEAL.\|.LMKG	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> G6PI_MOUSE @435
CATD_MOUSE	436	EALM.\|.MKGK	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> G6PI_MOUSE @436
CATE_MOUSE	436	EALM.\|.MKGK	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> G6PI_MOUSE @436
CATE_MOUSE	545	NGLI.\|.ISFI	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> G6PI_MOUSE @545

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)