TopFIND 4.0

P07203: Glutathione peroxidase 1

General Information

Protein names
- Glutathione peroxidase 1
- GPx-1
- GSHPx-1
- 1.11.1.9
- Cellular glutathione peroxidase
Gene names GPX1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P07203

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MCAARLAAAA AAAQSVYAFS ARPLAGGEPV SLGSLRGKVL LIENVASLUG TTVRDYTQMN 
        70         80         90        100        110        120 
ELQRRLGPRG LVVLGFPCNQ FGHQENAKNE EILNSLKYVR PGGGFEPNFM LFEKCEVNGA 
       130        140        150        160        170        180 
GAHPLFAFLR EALPAPSDDA TALMTDPKLI TWSPVCRNDV AWNFEKFLVG PDGVPLRRYS 
       190        200    
RRFQTIDIEP DIEALLSQGP SCA

Isoforms

- Isoform 2 of Glutathione peroxidase 1

Sequence View

        10         20         30         40         50         60 
MCAARLAAAA AAAQSVYAFS ARPLAGGEPV SLGSLRGKVL LIENVASLUG TTVRDYTQMN 
        70         80         90        100        110        120 
ELQRRLGPRG LVVLGFPCNQ FGHQENAKNE EILNSLKYVR PGGGFEPNFM LFEKCEVNGA 
       130        140        150        160        170        180 
GAHPLFAFLR EALPAPSDDA TALMTDPKLI TWSPVCRNDV AWNFEKFLVG PDGVPLRRYS 
       190        200    
RRFQTIDIEP DIEALLSQGP SCA



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P07203-1-unknown MCAARL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P07203-1-unknown MCAARL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt76378
    P07203-55-acetylation DYTQMN... 55 acetylation- N-TAILS Overall Laboratory Lange_Huesgen_et_al-RBC
    P07203-55-acetylation DYTQMN... 55 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt181452

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GPSCA 203 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)