P09086: POU domain, class 2, transcription factor 2

General Information

Protein names	- POU domain, class 2, transcription factor 2 - Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 - Octamer-binding protein 2 - Oct-2 - Octamer-binding transcription factor 2 - OTF-2
Gene names	POU2F2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P09086

7 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of POU domain, class 2, transcription factor 2 - Isoform 3 of POU domain, class 2, transcription factor 2 - Isoform 4 of POU domain, class 2, transcription factor 2 - Isoform 5 of POU domain, class 2, transcription factor 2

Sequence View

        10         20         30         40         50         60
MVHSSMGAPE IRMSKPLEAE KQGLDSPSEH TDTERNGPDT NHQNPQNKTS PFSVSPTGPS
        70         80         90        100        110        120
TKIKAEDPSG DSAPAAPLPP QPAQPHLPQA QLMLTGSQLA GDIQQLLQLQ QLVLVPGHHL
       130        140        150        160        170        180
QPPAQFLLPQ AQQSQPGLLP TPNLFQLPQQ TQGALLTSQP RAGLPTQAVT RPTLPDPHLS
       190        200        210        220        230        240
HPQPPKCLEP PSHPEEPSDL EELEQFARTF KQRRIKLGFT QGDVGLAMGK LYGNDFSQTT
       250        260        270        280        290        300
ISRFEALNLS FKNMCKLKPL LEKWLNDAET MSVDSSLPSP NQLSSPSLGF DGLPGRRRKK
       310        320        330        340        350        360
RTSIETNVRF ALEKSFLANQ KPTSEEILLI AEQLHMEKEV IRVWFCNRRQ KEKRINPCSA
       370        380        390        400        410        420
APMLPSPGKP ASYSPHMVTP QGGAGTLPLS QASSSLSTTV TTLSSAVGTL HPSRTAGGGG
       430        440        450        460        470
GGGGAAPPLN SIPSVTPPPP ATTNSTNPSP QGSHSAIGLS GLNPSTGPGL WWNPAPYQP         10         20         30         40         50         60
MVHSSMGAPE IRMSKPLEAE KQGLDSPSEH TDTERNGPDT NHQNPQNKTS PFSVSPTGPS
        70         80         90        100        110        120
TKIKAEDPSG DSAPAAPLPP QPAQPHLPQA QLMLTGSQLA GDIQQLLQLQ QLVLVPGHHL
       130        140        150        160        170        180
QPPAQFLLPQ AQQSQPGLLP TPNLFQLPQQ TQGALLTSQP RAGLPTQAVT RPTLPDPHLS
       190        200        210        220        230        240
HPQPPKCLEP PSHPEEPSDL EELEQFARTF KQRRIKLGFT QGDVGLAMGK LYGNDFSQTT
       250        260        270        280        290        300
ISRFEALNLS FKNMCKLKPL LEKWLNDAET MSVDSSLPSP NQLSSPSLGF DGLPGRRRKK
       310        320        330        340        350        360
RTSIETNVRF ALEKSFLANQ KPTSEEILLI AEQLHMEKEV IRVWFCNRRQ KEKRINPCSA
       370        380        390        400        410        420
APMLPSPGKP ASYSPHMVTP QGGAGTLPLS QASSSLSTTV TTLSSAVGTL HPSRTAGGGG
       430        440        450        460        470
GGGGAAPPLN SIPSVTPPPP ATTNSTNPSP QGSHSAIGLS GLNPSTGPGL WWNPAPYQP         10         20         30         40         50         60
MVHSSMGAPE IRMSKPLEAE KQGLDSPSEH TDTERNGPDT NHQNPQNKTS PFSVSPTGPS
        70         80         90        100        110        120
TKIKAEDPSG DSAPAAPLPP QPAQPHLPQA QLMLTGSQLA GDIQQLLQLQ QLVLVPGHHL
       130        140        150        160        170        180
QPPAQFLLPQ AQQSQPGLLP TPNLFQLPQQ TQGALLTSQP RAGLPTQAVT RPTLPDPHLS
       190        200        210        220        230        240
HPQPPKCLEP PSHPEEPSDL EELEQFARTF KQRRIKLGFT QGDVGLAMGK LYGNDFSQTT
       250        260        270        280        290        300
ISRFEALNLS FKNMCKLKPL LEKWLNDAET MSVDSSLPSP NQLSSPSLGF DGLPGRRRKK
       310        320        330        340        350        360
RTSIETNVRF ALEKSFLANQ KPTSEEILLI AEQLHMEKEV IRVWFCNRRQ KEKRINPCSA
       370        380        390        400        410        420
APMLPSPGKP ASYSPHMVTP QGGAGTLPLS QASSSLSTTV TTLSSAVGTL HPSRTAGGGG
       430        440        450        460        470
GGGGAAPPLN SIPSVTPPPP ATTNSTNPSP QGSHSAIGLS GLNPSTGPGL WWNPAPYQP         10         20         30         40         50         60
MVHSSMGAPE IRMSKPLEAE KQGLDSPSEH TDTERNGPDT NHQNPQNKTS PFSVSPTGPS
        70         80         90        100        110        120
TKIKAEDPSG DSAPAAPLPP QPAQPHLPQA QLMLTGSQLA GDIQQLLQLQ QLVLVPGHHL
       130        140        150        160        170        180
QPPAQFLLPQ AQQSQPGLLP TPNLFQLPQQ TQGALLTSQP RAGLPTQAVT RPTLPDPHLS
       190        200        210        220        230        240
HPQPPKCLEP PSHPEEPSDL EELEQFARTF KQRRIKLGFT QGDVGLAMGK LYGNDFSQTT
       250        260        270        280        290        300
ISRFEALNLS FKNMCKLKPL LEKWLNDAET MSVDSSLPSP NQLSSPSLGF DGLPGRRRKK
       310        320        330        340        350        360
RTSIETNVRF ALEKSFLANQ KPTSEEILLI AEQLHMEKEV IRVWFCNRRQ KEKRINPCSA
       370        380        390        400        410        420
APMLPSPGKP ASYSPHMVTP QGGAGTLPLS QASSSLSTTV TTLSSAVGTL HPSRTAGGGG
       430        440        450        460        470
GGGGAAPPLN SIPSVTPPPP ATTNSTNPSP QGSHSAIGLS GLNPSTGPGL WWNPAPYQP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P09086-1-unknown	MVHSSM...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P09086-1-unknown	MVHSSM...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85721
P09086-1-unknown	MVHSSM...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85722
P09086-1-unknown	MVHSSM...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85723
P09086-1-unknown	MVHSSM...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85724
P09086-2-	VHSSMG...	2		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P09086-2-	VHSSMG...	2		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P09086-2-	VHSSMG...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P09086-2-	VHSSMG...	2		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P09086-2-unknown	VHSSMG...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164925
P09086-2-unknown	VHSSMG...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164926
P09086-2-unknown	VHSSMG...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164927
P09086-2-unknown	VHSSMG...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164928
P09086-5-unknown	SMGAPE...	5	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174499
P09086-5-unknown	SMGAPE...	5	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174500
P09086-5-unknown	SMGAPE...	5	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174501
P09086-5-unknown	SMGAPE...	5	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174502
P09086-5-	SMGAPE...	5		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P09086-275-	SSLPSP...	275		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P09086-275-unknown	SSLPSP...	275	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176249
P09086-275-unknown	SSLPSP...	275	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176250
P09086-275-unknown	SSLPSP...	275	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176248
P09086-275-unknown	SSLPSP...	275	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176251

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NPSTGP	467	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81339
...NPSTGP	467	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92862
...NPSTGP	467	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92861
...APYQP	479	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...APYQP	479	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81340

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)